Taste Reward Processing in Pediatric Obesity

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01908153
Recruitment Status : Completed
First Posted : July 25, 2013
Last Update Posted : November 13, 2017
Information provided by (Responsible Party):
Cara Bohon, PhD, Stanford University

Brief Summary:
The study aims to provide a better understanding of the neural influence of eating behavior in the development of childhood obesity. Children ages 4-8 will be recruited to examine fMRI brain response to pictures that signal delivery of a chocolate milkshake and to the taste itself. The brain response will be compared to body mass index percentile scores for each child to help us determine whether brain differences present in adolescents and adults with obesity are present in young children.

Condition or disease
Pediatric Obesity

Study Type : Observational
Actual Enrollment : 30 participants
Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Taste Reward Processing in Pediatric Obesity
Study Start Date : September 2013
Actual Primary Completion Date : August 2015
Actual Study Completion Date : August 2015

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Children with BMI percentile of 85 or above.
Healthy Weight
Children with BMI percentile between 15 and 85.

Primary Outcome Measures :
  1. fMRI brain response to taste of chocolate milkshake [ Time Frame: Baseline ]
  2. fMRI brain response to picture cue [ Time Frame: Baseline ]

Information from the National Library of Medicine

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Ages Eligible for Study:   4 Years to 8 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Children ages 4-8

Inclusion Criteria:

  • ages 4-8
  • parent available to complete surveys in English

Exclusion Criteria:

  • no presence of metal in body
  • no claustrophobia
  • no psychiatric or neurological condition that will affect brain function

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01908153

United States, California
Stanford University Department of Psychiatry
Stanford, California, United States, 94305
Sponsors and Collaborators
Stanford University
Principal Investigator: Cara Bohon, PhD Stanford University

Publications of Results:
Responsible Party: Cara Bohon, PhD, Assistant Professor, Stanford University Identifier: NCT01908153     History of Changes
Other Study ID Numbers: UL1TR000093 ( U.S. NIH Grant/Contract )
First Posted: July 25, 2013    Key Record Dates
Last Update Posted: November 13, 2017
Last Verified: November 2017

Keywords provided by Cara Bohon, PhD, Stanford University:
Picture food type
Taste type

Additional relevant MeSH terms:
Pediatric Obesity
Nutrition Disorders
Body Weight
Signs and Symptoms