Prophylactic Antibiotic Treatment for Hand Lacerations Involving Flexor and/or Extensor Tendon
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|ClinicalTrials.gov Identifier: NCT01899781|
Recruitment Status : Unknown
Verified July 2013 by HaEmek Medical Center, Israel.
Recruitment status was: Not yet recruiting
First Posted : July 15, 2013
Last Update Posted : July 15, 2013
|Condition or disease||Intervention/treatment||Phase|
|Hand Laceration Tendon Involved Clean Laceration No Bone Involved||Drug: Antibiotic-Cefamezin||Phase 4|
Hand lacerations are divided to "complicated" which involves tendons, nerves, bones, and joints, and "simple" which involves only cutaneous and subcutaneous tissue.
prophylactic antibiotic should not be given in a clean simple lacerations, and should be given when a bone is involve (open fracture). But there is not enough data, weather prophylactic antibiotic treatment should be given when only tendons are involved. The investigators will examine 2 groups of 30 patients each with clean hand lacerations involving tendons. One group will be treated with prophylactic antibiotic and the other wont be treated, randomly. The investigators assume that the rate of wound infection wont be different between the 2 groups.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||60 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Prophylactic Antibiotic Treatment for Hand Lacerations Involving Flexor and/or Extensor Tendon|
|Study Start Date :||August 2013|
|Estimated Primary Completion Date :||January 2015|
|Active Comparator: with antibiotic and without antibiotic||
- rate of wound infections [ Time Frame: 2 years ]signs of wound/tissue infection, levels of WBC, ESR, CRP