Prophylactic Antibiotic Treatment for Hand Lacerations Involving Flexor and/or Extensor Tendon
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ClinicalTrials.gov Identifier: NCT01899781 |
Recruitment Status
: Unknown
Verified July 2013 by HaEmek Medical Center, Israel.
Recruitment status was: Not yet recruiting
First Posted
: July 15, 2013
Last Update Posted
: July 15, 2013
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Hand Laceration Tendon Involved Clean Laceration No Bone Involved | Drug: Antibiotic-Cefamezin | Phase 4 |
Hand lacerations are divided to "complicated" which involves tendons, nerves, bones, and joints, and "simple" which involves only cutaneous and subcutaneous tissue.
prophylactic antibiotic should not be given in a clean simple lacerations, and should be given when a bone is involve (open fracture). But there is not enough data, weather prophylactic antibiotic treatment should be given when only tendons are involved. The investigators will examine 2 groups of 30 patients each with clean hand lacerations involving tendons. One group will be treated with prophylactic antibiotic and the other wont be treated, randomly. The investigators assume that the rate of wound infection wont be different between the 2 groups.
Study Type : | Interventional (Clinical Trial) |
Estimated Enrollment : | 60 participants |
Intervention Model: | Single Group Assignment |
Masking: | None (Open Label) |
Primary Purpose: | Treatment |
Official Title: | Prophylactic Antibiotic Treatment for Hand Lacerations Involving Flexor and/or Extensor Tendon |
Study Start Date : | August 2013 |
Estimated Primary Completion Date : | January 2015 |
Arm | Intervention/treatment |
---|---|
Active Comparator: with antibiotic and without antibiotic |
Drug: Antibiotic-Cefamezin
Other Names:
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- rate of wound infections [ Time Frame: 2 years ]signs of wound/tissue infection, levels of WBC, ESR, CRP

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Ages Eligible for Study: | 13 Years to 75 Years (Child, Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- Hand laceration
- Tendon involeved
- Clean laceration
- No bone involved
Exclusion Criteria:
- Pregnant
- Children
- Immunocompremised patients
- "Dirty" lacerations
Responsible Party: | HaEmek Medical Center, Israel |
ClinicalTrials.gov Identifier: | NCT01899781 History of Changes |
Other Study ID Numbers: |
EMC-003812-CTIL |
First Posted: | July 15, 2013 Key Record Dates |
Last Update Posted: | July 15, 2013 |
Last Verified: | July 2013 |
Keywords provided by HaEmek Medical Center, Israel:
Lacerations Tendons Antobiotic |
Additional relevant MeSH terms:
Lacerations Wounds and Injuries Anti-Bacterial Agents |
Antibiotics, Antitubercular Anti-Infective Agents Antitubercular Agents |