Prophylactic Antibiotic Treatment for Hand Lacerations Involving Flexor and/or Extensor Tendon
Recruitment status was: Not yet recruiting
|Hand Laceration Tendon Involved Clean Laceration No Bone Involved||Drug: Antibiotic-Cefamezin||Phase 4|
|Study Design:||Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:||Prophylactic Antibiotic Treatment for Hand Lacerations Involving Flexor and/or Extensor Tendon|
- rate of wound infections [ Time Frame: 2 years ]signs of wound/tissue infection, levels of WBC, ESR, CRP
|Study Start Date:||August 2013|
|Estimated Primary Completion Date:||January 2015 (Final data collection date for primary outcome measure)|
|Active Comparator: with antibiotic and without antibiotic||
Hand lacerations are divided to "complicated" which involves tendons, nerves, bones, and joints, and "simple" which involves only cutaneous and subcutaneous tissue.
prophylactic antibiotic should not be given in a clean simple lacerations, and should be given when a bone is involve (open fracture). But there is not enough data, weather prophylactic antibiotic treatment should be given when only tendons are involved. The investigators will examine 2 groups of 30 patients each with clean hand lacerations involving tendons. One group will be treated with prophylactic antibiotic and the other wont be treated, randomly. The investigators assume that the rate of wound infection wont be different between the 2 groups.
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