Retraining Attention to Treat Alcohol Dependence and Social Anxiety (AMP)

This study has been completed.

Sponsor:

Collaborators:

Miami University

Brown University

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Information provided by (Responsible Party):

Joshua Magee, University of Cincinnati

ClinicalTrials.gov Identifier:

NCT01886716

First received: June 17, 2013

Last updated: December 15, 2014

Last verified: December 2014

History of Changes

Purpose

The purpose of this research is to test a computerized intervention for people with co-occurring social anxiety and alcohol dependence. The intervention seeks to reduce symptoms by shifting attention away from alcohol-relevant and/or socially threatening cues. The investigators expect that participants receiving alcohol or anxiety training will experience reductions in those specific symptoms compared to participants in a control condition. The investigators also expect that participants receiving combined alcohol and anxiety training will show the largest reductions in alcohol and anxiety symptoms, relative to participants in any other condition.

Condition	Intervention
Alcohol Drinking Anxiety Disorders	Behavioral: Anxiety Attention Training Behavioral: Alcohol Attention Training


Study Type:	Interventional
Study Design:	Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Parallel Assignment Masking: Double Blind (Subject, Outcomes Assessor) Primary Purpose: Treatment
Official Title:	Cognitive Bias Modification: A Novel Intervention for Alcohol Dependence and Social Anxiety

Resource links provided by NLM:

MedlinePlus related topics: Alcohol Alcoholism and Alcohol Abuse Anxiety

U.S. FDA Resources

Further study details as provided by University of Cincinnati:

Primary Outcome Measures:

Liebowitz Social Anxiety Scale [ Time Frame: End of Training (4 weeks) ] [ Designated as safety issue: No ]
30-Day Timeline Follow-back for Alcohol and Drugs [ Time Frame: End of Training (4 weeks) ] [ Designated as safety issue: No ]


Enrollment:	115
Study Start Date:	July 2013
Study Completion Date:	December 2014
Primary Completion Date:	December 2014 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
Experimental: Anxiety Attention Training only Participants will receive Anxiety Attention Training and placebo Alcohol training.	Behavioral: Anxiety Attention Training Anxiety Attention Training will preferentially direct participants' attention away from reminders of anxiety.
Experimental: Alcohol Attention Training only Participants will receive Alcohol Attention Training and placebo Anxiety training.	Behavioral: Alcohol Attention Training Alcohol Attention Training will preferentially direct participants' attention away from reminders of alcohol.
Experimental: Anxiety + Alcohol Attention Training Participants will receive both Anxiety Attention Training and Alcohol Attention Training.	Behavioral: Anxiety Attention Training Anxiety Attention Training will preferentially direct participants' attention away from reminders of anxiety. Behavioral: Alcohol Attention Training Alcohol Attention Training will preferentially direct participants' attention away from reminders of alcohol.
Placebo Comparator: Control Training Participants will receive placebo Anxiety Training and placebo Alcohol training.

Eligibility


Ages Eligible for Study:	18 Years and older (Adult, Senior)
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Current alcohol dependence
Elevated social anxiety symptoms
Willingness to consider cutting down on drinking

Exclusion Criteria:

Current psychosis
Unmanaged manic symptoms
Significant cognitive impairment
Other drug use in past month
Receiving cognitive behavioral therapy for alcohol use disorder or social anxiety
Unable to read

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01886716

Locations


United States, Ohio
University of Cincinnati Department of Family and Community Medicine
Cincinnati, Ohio, United States, 45206

Sponsors and Collaborators

University of Cincinnati

Miami University

Brown University

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Investigators


Principal Investigator:	Joshua C Magee, Ph.D.	University of Cincinnati

More Information


Responsible Party:	Joshua Magee, Assistant Research Professor, University of Cincinnati
ClinicalTrials.gov Identifier:	NCT01886716 History of Changes
Other Study ID Numbers:	1R21AA021151
Study First Received:	June 17, 2013
Last Updated:	December 15, 2014
Health Authority:	United States: Institutional Review Board United States: Federal Government

Keywords provided by University of Cincinnati:


Alcohol Abuse Alcohol Dependence Alcohol Drinking	Social Anxiety Social Phobia Anxiety Disorders

Additional relevant MeSH terms:


Anxiety Disorders Alcoholism Alcohol Drinking Mental Disorders Alcohol-Related Disorders Substance-Related Disorders Chemically-Induced Disorders	Drinking Behavior Ethanol Anti-Infective Agents, Local Anti-Infective Agents Central Nervous System Depressants Physiological Effects of Drugs

ClinicalTrials.gov processed this record on September 28, 2016

To Top