Retraining Attention to Treat Alcohol Dependence and Social Anxiety (AMP)
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ClinicalTrials.gov Identifier: NCT01886716 |
Recruitment Status
:
Completed
First Posted
: June 26, 2013
Results First Posted
: December 28, 2016
Last Update Posted
: December 28, 2016
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Alcohol Drinking Anxiety Disorders | Behavioral: Anxiety Attention Training Behavioral: Alcohol Attention Training Behavioral: Control Training | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 115 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Double (Participant, Outcomes Assessor) |
Primary Purpose: | Treatment |
Official Title: | Cognitive Bias Modification: A Novel Intervention for Alcohol Dependence and Social Anxiety |
Study Start Date : | July 2013 |
Actual Primary Completion Date : | December 2014 |
Actual Study Completion Date : | December 2014 |
Arm | Intervention/treatment |
---|---|
Experimental: Anxiety Attention Training only
Participants will receive Anxiety Attention Training and placebo Alcohol training.
|
Behavioral: Anxiety Attention Training
Anxiety Attention Training will preferentially direct participants' attention away from reminders of anxiety.
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Experimental: Alcohol Attention Training only
Participants will receive Alcohol Attention Training and placebo Anxiety training.
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Behavioral: Alcohol Attention Training
Alcohol Attention Training will preferentially direct participants' attention away from reminders of alcohol.
|
Experimental: Anxiety + Alcohol Attention Training
Participants will receive both Anxiety Attention Training and Alcohol Attention Training.
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Behavioral: Anxiety Attention Training
Anxiety Attention Training will preferentially direct participants' attention away from reminders of anxiety.
Behavioral: Alcohol Attention Training
Alcohol Attention Training will preferentially direct participants' attention away from reminders of alcohol.
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Placebo Comparator: Control Training
Participants will receive placebo Anxiety Training and placebo Alcohol training.
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Behavioral: Control Training
Placebo Anxiety Training and Placebo Alcohol Training will not preferentially direct participants' attention away from reminders of anxiety or alcohol.
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- Liebowitz Social Anxiety Scale [ Time Frame: Baseline, weekly throughout the 4-week trial, and in the follow-up sessions (1 week and 1 month follow-ups) ]The experimenter-administered Liebowitz Social Anxiety Scale (Liebowitz, 1987) was the primary measure to assess social anxiety symptoms. This well-validated instrument assesses fear and avoidance across a range of 24 social and performance situations during the course of the previous week. A total LSAS score was computed, ranging from 0 (no fear or avoidance) to 144 (the greatest level of fear and avoidance).
- The Daily Drinking Questionnaire [ Time Frame: Baseline, weekly throughout the 4-week trial, and in the follow-up sessions (1 week and 1 month follow-ups) ]The Daily Drinking Questionnaire (Collins, Parks, & Marlatt, 1985) was the primary measure used to assess weekly alcohol consumption. This calendar-based measure was administered by the experimenter once per week to monitor changes in symptoms. The measure assessed the total number of drinks in the past week.

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Ages Eligible for Study: | 18 Years and older (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Current alcohol dependence
- Elevated social anxiety symptoms
- Willingness to consider cutting down on drinking
Exclusion Criteria:
- Current psychosis
- Unmanaged manic symptoms
- Significant cognitive impairment
- Other drug use in past month
- Receiving cognitive behavioral therapy for alcohol use disorder or social anxiety
- Unable to read

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01886716
United States, Ohio | |
University of Cincinnati Department of Family and Community Medicine | |
Cincinnati, Ohio, United States, 45206 |
Principal Investigator: | Joshua C Magee, Ph.D. | University of Cincinnati |
Responsible Party: | Joshua Magee, Assistant Research Professor, University of Cincinnati |
ClinicalTrials.gov Identifier: | NCT01886716 History of Changes |
Other Study ID Numbers: |
1R21AA021151 ( U.S. NIH Grant/Contract ) |
First Posted: | June 26, 2013 Key Record Dates |
Results First Posted: | December 28, 2016 |
Last Update Posted: | December 28, 2016 |
Last Verified: | December 2016 |
Individual Participant Data (IPD) Sharing Statement: | |
Plan to Share IPD: | No |
Keywords provided by Joshua Magee, University of Cincinnati:
Alcohol Abuse Alcohol Dependence Alcohol Drinking |
Social Anxiety Social Phobia Anxiety Disorders |
Additional relevant MeSH terms:
Anxiety Disorders Alcoholism Alcohol Drinking Mental Disorders Alcohol-Related Disorders Substance-Related Disorders Chemically-Induced Disorders |
Drinking Behavior Ethanol Anti-Infective Agents, Local Anti-Infective Agents Central Nervous System Depressants Physiological Effects of Drugs |