We are updating the design of this site. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Morphological Analysis of the Pineal Gland in Pediatric Retinoblastoma Patients Using Magnetic Resonance Imaging

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01884194
First Posted: June 21, 2013
Last Update Posted: December 29, 2015
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Thi Thai Hien Pham, Charite University, Berlin, Germany
  Purpose
MRI is useful for diagnosing pinealoblastoma in retinoblastoma patients

Condition
Retinoblastoma Pineoblastoma

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Morphological Analysis of the Pineal Gland in Pediatric Retinoblastoma Patients Using Magnetic Resonance Imaging

Resource links provided by NLM:


Further study details as provided by Thi Thai Hien Pham, Charite University, Berlin, Germany:

Primary Outcome Measures:
  • Malignancy criteria of pineal gland [ Time Frame: clinical follow-up 1-year after baseline imaging ]
    size of pineal gland solid or cystic component (all at baseline)


Enrollment: 80
Study Start Date: November 2013
Study Completion Date: February 2015
Primary Completion Date: December 2014 (Final data collection date for primary outcome measure)
Groups/Cohorts
Retinoblastoma patients
patients with diagnosed retinoblastoma
non-retinoblastoma patients
aged matched control cohort without the diagnosis of ocular or brain tumor

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   up to 50 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
pediatric patients with retinoblastoma
Criteria

Inclusion Criteria:

  • diagnosis of retinoblastoma
  • brain MRI available

Exclusion Criteria:

  • insufficient quality of brain MRI
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01884194


Locations
Germany
Charite Hospital Berlin
Berlin, Germany, 12200
Sponsors and Collaborators
Charite University, Berlin, Germany
  More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Thi Thai Hien Pham, doctoral candidate, Charite University, Berlin, Germany
ClinicalTrials.gov Identifier: NCT01884194     History of Changes
Other Study ID Numbers: RTB_0305_outcome
First Submitted: May 24, 2013
First Posted: June 21, 2013
Last Update Posted: December 29, 2015
Last Verified: December 2015

Keywords provided by Thi Thai Hien Pham, Charite University, Berlin, Germany:
retinoblastoma
pineoblastoma

Additional relevant MeSH terms:
Retinoblastoma
Pinealoma
Neoplasms, Neuroepithelial
Neuroectodermal Tumors
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
Neoplasms
Neoplasms, Glandular and Epithelial
Neoplasms, Nerve Tissue
Retinal Neoplasms
Eye Neoplasms
Neoplasms by Site
Eye Diseases
Retinal Diseases
Brain Neoplasms
Central Nervous System Neoplasms
Nervous System Neoplasms
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases