Morphological Analysis of the Pineal Gland in Pediatric Retinoblastoma Patients Using Magnetic Resonance Imaging

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Thi Thai Hien Pham, Charite University, Berlin, Germany
ClinicalTrials.gov Identifier:
NCT01884194
First received: May 24, 2013
Last updated: December 28, 2015
Last verified: December 2015
  Purpose
MRI is useful for diagnosing pinealoblastoma in retinoblastoma patients

Condition
Retinoblastoma
Pineoblastoma

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Morphological Analysis of the Pineal Gland in Pediatric Retinoblastoma Patients Using Magnetic Resonance Imaging

Resource links provided by NLM:


Further study details as provided by Charite University, Berlin, Germany:

Primary Outcome Measures:
  • Malignancy criteria of pineal gland [ Time Frame: clinical follow-up 1-year after baseline imaging ] [ Designated as safety issue: No ]
    size of pineal gland solid or cystic component (all at baseline)


Enrollment: 80
Study Start Date: November 2013
Study Completion Date: February 2015
Primary Completion Date: December 2014 (Final data collection date for primary outcome measure)
Groups/Cohorts
Retinoblastoma patients
patients with diagnosed retinoblastoma
non-retinoblastoma patients
aged matched control cohort without the diagnosis of ocular or brain tumor

  Eligibility

Ages Eligible for Study:   up to 50 Years   (Child, Adult)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
pediatric patients with retinoblastoma
Criteria

Inclusion Criteria:

  • diagnosis of retinoblastoma
  • brain MRI available

Exclusion Criteria:

  • insufficient quality of brain MRI
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01884194

Locations
Germany
Charite Hospital Berlin
Berlin, Germany, 12200
Sponsors and Collaborators
Charite University, Berlin, Germany
  More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Thi Thai Hien Pham, doctoral candidate, Charite University, Berlin, Germany
ClinicalTrials.gov Identifier: NCT01884194     History of Changes
Other Study ID Numbers: RTB_0305_outcome 
Study First Received: May 24, 2013
Last Updated: December 28, 2015
Health Authority: Germany: Ethics Commission

Keywords provided by Charite University, Berlin, Germany:
retinoblastoma
pineoblastoma

Additional relevant MeSH terms:
Retinoblastoma
Pinealoma
Neoplasms, Neuroepithelial
Neuroectodermal Tumors
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
Neoplasms
Neoplasms, Glandular and Epithelial
Neoplasms, Nerve Tissue
Retinal Neoplasms
Eye Neoplasms
Neoplasms by Site
Eye Diseases
Retinal Diseases
Brain Neoplasms
Central Nervous System Neoplasms
Nervous System Neoplasms
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases

ClinicalTrials.gov processed this record on July 21, 2016