Exercise-induced Hypoalgesia After Comparative Forms of Exercise
|ClinicalTrials.gov Identifier: NCT01883895|
Recruitment Status : Completed
First Posted : June 21, 2013
Results First Posted : July 24, 2017
Last Update Posted : July 24, 2017
|Condition or disease||Intervention/treatment||Phase|
|Pain||Device: Forgionei-Barber pressure-pain stimulator Other: Concentric Exercise Other: isometric exercise||Not Applicable|
Show Detailed Description
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||34 participants|
|Intervention Model:||Single Group Assignment|
|Intervention Model Description:||three treatment design, all participants will perform two exercise sessions (isometric exercise, concentric exercise), as well as a control session in a randomized manner. (This is not a cross-over design as each participant will have their own randomized order of sessions of exercise & control sessions.)|
|Masking:||None (Open Label)|
|Official Title:||Exercise-induced Hypoalgesia After Comparative Forms of Anaerobic Training in Healthy Adults|
|Study Start Date :||June 2013|
|Actual Primary Completion Date :||May 2014|
|Actual Study Completion Date :||May 2014|
Concentric exercise: subject will utilize a dumbbell with elbow flexion exercise.
Isometric exercise: Subjects will perform 5 sets of sustained muscle contraction.
Control: Subjects will undergo a control arm where they will rest for approximately 10 minutes.
Pain testing conducted by Forgionei-Barber pressure pain-stimulator for both the control and exercise treatments.
Device: Forgionei-Barber pressure-pain stimulator
Pain testing will be conducted using a Forgioni-Barber pressure-pain stimulator to deliver 3000-gm force to the middle digit of the non-dominant middle finger for up to 120 seconds. During stimulation, subjects will press a button attached to a timer when the pressure stimulus first becomes painful (pain threshold) and will also rate their perceived pain intensity using a 0-100 numeric pain rating scale at 20 second intervals during the 2 minute exposure to the pressure stimulus. This validated protocol has been used in previous research by investigators in this study. This will be used for both exercise sessions and the control session. Forgionei-Barber pressure-pain stimulator will be used.Other: Concentric Exercise
Concentric testing will utilize a dumbbell with elbow flexion exercise. Subjects will perform 5 sets of 20 reps at 30% MVC. Pain testing will be conducted using a Forgionei-Barber pressure-pain stimulator immediately before and after the exercise.Other: isometric exercise
When undergoing isometric exercise, subjects will perform 5 sets of sustained muscle contraction for 65 seconds using a hand-grip dynamometer. Pain testing will be conducted using a Forgionei-Barber pressure-pain stimulator immediately before and after the exercise.
- Change in Pain Intensity Ratings (0-100 Pain Scale) [ Time Frame: Average pain rating over 120 seconds ]
Subjects will rate pain intensity using a 0 (no pain) to 100 (most intense pain imaginable) pain rating scale before and after application of a validated pressure stimulator immediately prior to, and after exercise.
Ratings will be recorded at 20 second intervals following each administration of the pressure stimulator for a total of 120 seconds. The ratings will then be averaged over all the time points.
- Pain Threshold [ Time Frame: We will monitor the subject's reported pain thresholds during the two minute interval that the pressure stimulus is applied. Expected average is less than one minute. ]Subjects will press a button attached to a timer out of view of the subject when the pressure stimulus first becomes painful. This will utilize a protocol recognized as a validated measurement of pain threshold.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01883895
|United States, Wisconsin|
|University of Wisconsin Hospitals and Clinics|
|Madison, Wisconsin, United States, 53705|
|Principal Investigator:||Nalini Sehgal, MD||University of Wisconsin Dept Ortho/Rehab|
|Study Director:||ben rawson, DO||University of Wisconsin Dept Ortho/Rehab|