Efficacy of COMB (Comprehensive Behavioral) Model of Treatment of Trichotillomania

This study has been completed.
Trichotillomania Learning Center
Information provided by (Responsible Party):
David A. F. Haaga, American University
ClinicalTrials.gov Identifier:
First received: June 10, 2013
Last updated: April 14, 2015
Last verified: April 2015
This pilot study is being conducted in order to help make the case for later, more systematic research on the effectiveness of the Comprehensive Behavioral (COMB) model of treating trichotillomania (compulsive hair pulling). The goals are to standardize COMB treatment techniques in the form of a clear written manual for therapists; determine whether therapists can use these guidelines in a consistent manner in making treatment decisions; develop and test the reliability of measures of how well therapists are conducting the treatment; and collect preliminary data on the acceptability of the treatment to patients.

Condition Intervention
Hair-Pulling Disorder
Behavioral: COMB

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Treatment Development Study of the COMB Model of Trichotillomania

Resource links provided by NLM:

Further study details as provided by American University:

Primary Outcome Measures:
  • Massachusetts General Hospital Hairpulling Scale (MGH-HS) [ Time Frame: 12 weeks ] [ Designated as safety issue: No ]
    Improvement in hair pulling symptoms

Enrollment: 16
Study Start Date: January 2013
Primary Completion Date: January 2015 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: COMB Behavioral: COMB


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • 18 years or older
  • Primary Diagnostic and Statistical Manual, Fifth Edition (DSM-5) diagnosis of Trichotillomania (TTM)

Exclusion Criteria:

  • Current suicidality or severe depression
  • Current psychosis
  • Current alcohol or substance abuse
  • Concurrent psychotherapy for TTM
  • Psychotropic meds (for any disorder) that have not been stable for >4 weeks
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01878110

United States, District of Columbia
American University
Washington, District of Columbia, United States
Sponsors and Collaborators
American University
Trichotillomania Learning Center
  More Information

Responsible Party: David A. F. Haaga, Professor of Psychology, American University
ClinicalTrials.gov Identifier: NCT01878110     History of Changes
Other Study ID Numbers: TLC COMB Pilot Study  TLC 
Study First Received: June 10, 2013
Last Updated: April 14, 2015
Health Authority: United States: Institutional Review Board

Keywords provided by American University:
Hair pulling
Behavior therapy

Additional relevant MeSH terms:
Disruptive, Impulse Control, and Conduct Disorders
Mental Disorders

ClinicalTrials.gov processed this record on May 25, 2016