C-GLOVES: the Effectiveness of Compression Gloves in Arthritis (C-GLOVES)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01874067
Recruitment Status : Completed
First Posted : June 10, 2013
Last Update Posted : March 3, 2016
Information provided by (Responsible Party):
Alison Hammond, University of Salford

Brief Summary:

This is a collaborative study with 11 Occupational Therapy (OT) departments in North-West England. The OTs provide arthritis gloves to 25% of out-patients with inflammatory, rheumatoid and osteoarthritis. The pressure applied by the glove(s) may help relieve hand pain, swelling and stiffness. People find they help but there is little research testing this. Of the five small studies published: two found little or no benefit; one found similar effects from arthritis and ordinary thermal gloves; two found some benefits. Testing if gloves work helps therapists and patients judge if they will help.

This is a feasibility study to help us plan a future trial testing if arthritis gloves work for people with arthritis. We aim to find out: the rate we can recruit people to the study; if OTs can assess people's hands and provide gloves as agreed; how many people do we need to take part in a trial; what do people think (if any) is the gloves' most important effect and how long should we test them for? We will analyse the data to see what effect the gloves have.

The study will last 12 months. People will get arthritis gloves as part of their usual care. The OTs have agreed a standard way of assessing and providing the gloves to ensure best practice across departments. The assessments include: difficulties using hands, pain and stiffness levels, and measuring hand and finger joint size and movement. People can take part if they: have one of the three types of arthritis; are willing to wear Isotoner three-quarter length gloves; can attend the usual 4 week review appointment for re-assessment; will allow us to use their anonymized hand assessments. We will also interview some people about their views of the assessment and their treatment. Each patient will be involved for 4-8 weeks.

Condition or disease Intervention/treatment
Inflammatory Arthritis Rheumatoid Arthritis Hand Osteoarthritis Device: Arthritis glove

  Show Detailed Description

Study Type : Observational
Actual Enrollment : 75 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: C-GLOVES: an Evaluation of the Effectiveness of Compression Gloves in Arthritis: a Feasibility Study
Study Start Date : October 2013
Actual Primary Completion Date : June 2014
Actual Study Completion Date : March 2015

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Arthritis

Group/Cohort Intervention/treatment
Arthritis glove
Early inflammatory, rheumatoid or hand osteoarthritis with hand/wrist swelling and pain
Device: Arthritis glove
Isotoner three-quarter finger arthritis glove

Primary Outcome Measures :
  1. Hand pain on movement [ Time Frame: 4 weeks ]
    10 point numeric rating scale of hand pain during moderate activities (eg housework, gardening, work) with end points of no to severe pain

Secondary Outcome Measures :
  1. Measure of Activity Performance in the Hand: patient reported outcome [ Time Frame: 4 weeks ]
    patient reported outcome of hand function

  2. Grip Ability Test [ Time Frame: 4 weeks ]
    objective measure of hand function

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 100 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Rheumatology Occupational Therapy and Hand Therapy out-patient departments

Inclusion Criteria:

  • experiencing hand pain and swelling

Exclusion Criteria:

  • unable to give informed consent

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01874067

United Kingdom
Occupational Therapy, Leighton Hospital
Crewe, Cheshire, United Kingdom, CW1 4QJ
Occupational Therapy, Victoria Infirmary
Northwich, Cheshire, United Kingdom, CW8 1AW
Occupational Therapy Department, Stepping Hill Hospital
Stockport, Greater Manchester, United Kingdom, SK2 7JE
Ocupational Therapy, St Helens Hospital
St Helens, Knowsley, United Kingdom, WA9 3DA
Occupational Therapy, Southport District General Hospital
Southport, Merseyside, United Kingdom, PR8 6PN
Sponsors and Collaborators
University of Salford
Principal Investigator: Alison Hammond, PhD University of Salford

Study Data/Documents: Clinical Study Report  This link exits the site
Identifier: 35110
Conference Abstract: Hammond, A, Prior, Y, Jones, V, Dooley, M, Hough, Y and Jacklin, A 2015, 'A pre-post test pilot trial of compression gloves in early inflammatory and rheumatoid arthritis' , Rheumatology, 54 (S1) , i111-112

Hammond A, Prior Y, Jones V, Dooley M, Hough Y, Jacklin A. A Pre-Test Post-test pilot trial of compression gloves in early inflammatory and rheumatoid arthritis. Rheumatology 54(S1):i111-112, 2015. doi:10.1093/rheumatology/kev089.045
Hammond A, Prior Y, Jones V, Dooley M, Hough Y, Jacklin A. The Effect of Compression Gloves in Hand Osteoarthritis: A Pre-Pest-Test Trial. Arthritis and Rheumatism 66(11 Supplement): S436, 2014

Responsible Party: Alison Hammond, Professor in Rheumatology Rehabilitation, University of Salford Identifier: NCT01874067     History of Changes
Other Study ID Numbers: C-GLOVES v2 26.7.13
13/EM/0253 ( Other Identifier: NHS Research Ethics Committee (UK) )
First Posted: June 10, 2013    Key Record Dates
Last Update Posted: March 3, 2016
Last Verified: March 2016
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Additional relevant MeSH terms:
Arthritis, Rheumatoid
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases
Connective Tissue Diseases
Autoimmune Diseases
Immune System Diseases