Transplantation of Bone Marrow Mesenchymal Stem Cell in Crohn's Disease
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|ClinicalTrials.gov Identifier: NCT01874015|
Recruitment Status : Recruiting
First Posted : June 10, 2013
Last Update Posted : April 27, 2017
|Condition or disease||Intervention/treatment||Phase|
|Crohn's Disease||Biological: mesenchymal cell transplantation Biological: mesenchymal cell and fibroblast injection||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||10 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Transplantation of Bone Marrow Mesenchymal Stem Cell in Moderate to Severe Fistulizing Crohn's Disease|
|Actual Study Start Date :||February 2013|
|Estimated Primary Completion Date :||December 2017|
|Estimated Study Completion Date :||February 2018|
Active Comparator: mesenchymal cell and fibroblast transplantaion
The patients with crohn's disease who underwent mesenchymal cell and fibroblast injection.
Biological: mesenchymal cell and fibroblast injection
Transplantation of mesenchymal cell and fibroblast in patients with crohn's disease.
Active Comparator: mesenchymal cell transplantaion
The patients with Crohn's disease who underwent mesenchymal cell transplantation.
Biological: mesenchymal cell transplantation
Mesenchymal cell transplantation in patients with Crohn's disease.
- fistula closure [ Time Frame: 4months ]Evaluation the fistula closure after mesenchymal cell transplantation in patients with crohn's disease.
- CDAI [ Time Frame: 4months ]Evaluation the decrease of CDAI after mesenchymal cell transplantation.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01874015
|Contact: Nasser Aghdami, MD,PhD||+9823562000 ext email@example.com|
|Contact: Leila Arab, MD||+9823562000 ext 414||Leara91@gmail.com|
|Iran, Islamic Republic of|
|Tehran, Iran, Islamic Republic of|
|Contact: Nasser Aghdami, MD,PhD|
|Principal Investigator: Massoud Vosough, MD,PhD|
|Sub-Investigator: vagihe azimian, MSc|
|Study Chair:||Hamid Gourabi, PhD||Head of Royan Institute|
|Study Director:||Nasser Aghdami, MD,PhD||Head of Royan department of degenerative medicine,Head of Royan celltherapy center|
|Study Director:||Mahdi Mohammad Nejhad, MD||TUMS DDRI|