DTI of the Brain and Cervical Spine: Evaluation in Normal Subjects and Patients With Cervical Spondylotic Myelopathy
|ClinicalTrials.gov Identifier: NCT01868958|
Recruitment Status : Completed
First Posted : June 5, 2013
Last Update Posted : July 15, 2015
|Condition or disease|
|Cervical Spondylosis With Myelopathy|
Show Detailed Description
|Study Type :||Observational|
|Actual Enrollment :||26 participants|
|Observational Model:||Case Control|
|Official Title:||Diffusion Tensor Imaging of the Brain and Cervical Spine: Evaluation of Reproducibility in Normal Subjects and Diagnostic Utility in Patients With Cervical Spondylotic Myelopathy|
|Study Start Date :||January 2013|
|Primary Completion Date :||June 2015|
|Study Completion Date :||June 2015|
Subjects with clinical indications of cervical spondylotic myelopathy (CSM).
Aged matched to the CSM group but with no signs of CSM
- Diffusion properties of the spinal cord [ Time Frame: The diffusion properties are measured in a single imaging session lasting approximately 50 minutes. ]
Two parameters characterizing the diffusion of water in the spinal cord will be studied.
- The fractional anisotropy reflects the orientational motion of water and the average value will be assessed over the length of the cervical spine for both the control and patient groups. This quantity has no units.
- The trace of the diffusion tensor. This measures the mean diffusivity of the water in the spinal cord and is measured in m^2/sec.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01868958
|United States, Georgia|
|Center for Systems Imaging (CSI), Emory University|
|Atlanta, Georgia, United States, 30329|
|Principal Investigator:||Richard A Jones, PhD||Department of Radiology, Emory University|