Spectral Dynamics and Speech Understanding by Hearing Impaired People
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| ClinicalTrials.gov Identifier: NCT01867515 |
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Recruitment Status :
Completed
First Posted : June 4, 2013
Results First Posted : April 26, 2018
Last Update Posted : April 26, 2018
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Sponsor:
VA Office of Research and Development
Information provided by (Responsible Party):
VA Office of Research and Development
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Brief Summary:
The purpose of this program of research is to understand the perception of the dynamic spectral properties of speech by hearing-impaired listeners, with the long-term goal of improving speech understanding by these individuals in adverse listening conditions. The proposed research compares the performance of normally-hearing and hearing-impaired listeners on measures of speech understanding in the presence of different types of signal distortion and speech understanding of signals with enhanced spectral dynamics. A computational model based on the amount of potential information available in speech will be used to quantify differences in speech intelligibility due to hearing status and stimulus characteristics.
| Condition or disease | Intervention/treatment | Phase |
|---|---|---|
| Hearing Loss, Sensorineural | Other: Acoustic distortion of speech | Not Applicable |
This is a behavioral study of human auditory perception. Each experiment in this study involves prospective data collection from three types of listeners. The experimental listeners will be people with sensorineural hearing loss and the control listeners will either be subjects with normal hearing or normal-hearing listeners for whom hearing loss will be simulated through the use of a spectrally-shaped broadband noise. The tasks of the subjects in this study involve either listening to synthesized sounds over earphones while seated comfortably in a sound-treated booth, and making responses indicating the subject's auditory perception of these sounds by touching specific areas on a touch-screen terminal; or, listening to recorded, acoustically modified syllables, words, or sentences over earphones and making responses indicating the subject's identification.
| Study Type : | Interventional (Clinical Trial) |
| Actual Enrollment : | 50 participants |
| Allocation: | Non-Randomized |
| Intervention Model: | Single Group Assignment |
| Masking: | None (Open Label) |
| Primary Purpose: | Other |
| Official Title: | Spectral Dynamics and Speech Understanding by Hearing Impaired People |
| Study Start Date : | August 2013 |
| Actual Primary Completion Date : | September 2016 |
| Actual Study Completion Date : | September 2016 |
Resource links provided by the National Library of Medicine
Genetics Home Reference related topics:
Nonsyndromic hearing loss
MedlinePlus related topics:
Hearing Disorders and Deafness
| Arm | Intervention/treatment |
|---|---|
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Active Comparator: Younger normally-hearing listeners
Participants with auditory thresholds within the normal limits.
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Other: Acoustic distortion of speech |
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Active Comparator: Hearing-impaired listeners
individuals with bilateral sensorineural hearing losses with thresholds between 25 and 70 dB HL and no losses greater than 70 dB HL at frequencies of 4000 Hz or below
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Other: Acoustic distortion of speech |
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Active Comparator: Older normally-hearing listeners
Participants with auditory thresholds within the normal limits.
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Other: Acoustic distortion of speech |
Primary Outcome Measures :
- Percent Correct Words Identified [ Time Frame: average of two blocks per condition obtained over the course of up to three 2-hour visits, spaced an average of one week apart ]The experimental approach compares speech identification performance among younger, normally-hearing listeners, older normally-hearing listeners and hearing-impaired listeners. Tasks will be carried out in quiet and in the presence of continuous, speech-shaped background noise. The investigators compared the understanding of unprocessed stimuli with 1) time-compressed stimuli, 2) time-compressed stimuli expanded in time via gaps and 3) uncompressed stimuli where portions of the signal were replaced with silence. Experimental metrics were percentage of correct/incorrect speech identification in each listening condition.
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| Ages Eligible for Study: | 18 Years to 65 Years (Adult, Older Adult) |
| Sexes Eligible for Study: | All |
| Accepts Healthy Volunteers: | Yes |
Criteria
Inclusion Criteria:
- individuals with hearing thresholds of 20 dB HL or better at all octave frequencies between 250 Hz and 4000 Hz
- or, individuals with bilateral sensorineural hearing losses with thresholds between 25 and 70 dB HL and no losses greater than 70 dB HL at frequencies of 4000 Hz or below
Exclusion Criteria:
- a conductive hearing impairment or other otological pathology
- hearing thresholds greater than 70 dB HL at any frequencies of 4000 Hz or below or pure-tone averages (averaged across 500, 1000, and 2000 Hz) of greater than 65 dB HL
- bilateral differences greater than 20 dB at any frequency below 4000 Hz
- an inability to complete the experimental tasks
Information from the National Library of Medicine
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01867515
Locations
| United States, Oregon | |
| VA Portland Health Care System, Portland, OR | |
| Portland, Oregon, United States, 97239 | |
Sponsors and Collaborators
VA Office of Research and Development
Investigators
| Principal Investigator: | Michelle R Molis, PhD | VA Portland Health Care System, Portland, OR |
| Responsible Party: | VA Office of Research and Development |
| ClinicalTrials.gov Identifier: | NCT01867515 History of Changes |
| Other Study ID Numbers: |
C1020-R 5I01RX001020-03 ( U.S. NIH Grant/Contract ) |
| First Posted: | June 4, 2013 Key Record Dates |
| Results First Posted: | April 26, 2018 |
| Last Update Posted: | April 26, 2018 |
| Last Verified: | April 2018 |
| Individual Participant Data (IPD) Sharing Statement: | |
| Plan to Share IPD: | Undecided |
| Studies a U.S. FDA-regulated Drug Product: | No | |
| Studies a U.S. FDA-regulated Device Product: | No | |
Keywords provided by VA Office of Research and Development:
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Hearing Hearing Loss, sensorineural Speech Perception |
Additional relevant MeSH terms:
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Hearing Loss Deafness Hearing Loss, Sensorineural Hearing Disorders Ear Diseases |
Otorhinolaryngologic Diseases Sensation Disorders Neurologic Manifestations Nervous System Diseases Signs and Symptoms |