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Comparison of Optic Nerve Sheath Diameter on Retrobulbar Ultrasonography Before and After Drainage of Cerebrospinal Fluid in Pediatric Patient With Hydrocephalus

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified May 2013 by Yonsei University.
Recruitment status was:  Recruiting
Information provided by (Responsible Party):
Yonsei University Identifier:
First received: May 22, 2013
Last updated: May 26, 2013
Last verified: May 2013
Studies in patients with intracranial hypertension have shown a good relationship between optic nerve sheath diameter measured by retrobulbar ultrasound and invasively measured intracranial pressure. The aim of this study was to evaluate changes in optic nerve sheath diameter before and after drainage of cerebrospinal fluid in patients with hydrocephalus.

Condition Intervention
Hydrocephalus Procedure: retrobulbar ultrasound

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Retrospective

Resource links provided by NLM:

Further study details as provided by Yonsei University:

Primary Outcome Measures:
  • both optic nerve sheath diameter (the posterior 3mm of the papilla) [ Time Frame: For day 1 from induction of general anesthesia to average 15 min after recovery of general anesthesia ]

Estimated Enrollment: 38
Study Start Date: May 2013
Estimated Study Completion Date: May 2014
Estimated Primary Completion Date: May 2014 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
both optic nerve sheath diameter Procedure: retrobulbar ultrasound
both optic nerve sheath diameter (the posterior 3mm of the papilla), 5 individual measurement


Ages Eligible for Study:   1 Year to 19 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
patient with hydrocephalus

Inclusion Criteria:

  1. ASA Ⅰ-Ⅱ
  2. aged between 1 and 19 year
  3. hydrocephalus
  4. general anesthesia for undergoing drainage of cerebrospinal fluid

Exclusion Criteria:

1. an anatomical or functional abnormality in optic nerve

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01865149

Contact: Hyunzu Kim, MD 82-2-2228-2422

Korea, Republic of
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Recruiting
Seoul, Korea, Republic of, 120-752
Contact: Hyunzu Kim, MD    82-2-2228-2422   
Sponsors and Collaborators
Yonsei University
  More Information

Responsible Party: Yonsei University Identifier: NCT01865149     History of Changes
Other Study ID Numbers: 1-2013-0022
Study First Received: May 22, 2013
Last Updated: May 26, 2013

Keywords provided by Yonsei University:
Optic nerve sheath diameter
Intracranial hypertension

Additional relevant MeSH terms:
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases processed this record on September 21, 2017