Physiological Effects of Deferred Cord Clamping (DoppCord)
|ClinicalTrials.gov Identifier: NCT01864421|
Recruitment Status : Terminated (New data in public domain suggested continuing study not ethical)
First Posted : May 29, 2013
Last Update Posted : May 17, 2018
|Condition or disease|
|Deferred Umbilical Cord Clamping|
Show Detailed Description
|Study Type :||Observational|
|Actual Enrollment :||15 participants|
|Official Title:||Delivery Room and Postnatal Assessment of the Physiological Effects of Deferred Cord Clamping on the Newborn: A Feasibility Study|
|Study Start Date :||May 2013|
|Actual Primary Completion Date :||May 2018|
|Actual Study Completion Date :||May 2018|
Infants undergoing a deferring of umbilical cord clamping for 30 seconds or more
Immeadiate Cord Clamping
Infants undergoing immediate umbilical cord clamping in the first 20 seconds of life.
- Quantification of blood flow in the umbilical cord or skin [ Time Frame: For Doppler the umbilical cord will be scanned until it is clamped (up to 3 minutes). Blood flow to the skin will be measured for up to 20 minutes as long as this is not interfering with normal clinical care. ]The use of either Doppler ultrasound or a photoplethysmographic (PPG) sensor at delivery to measure either blood flow in the umbilical cord or the skin.
- To assess the cardiovascular status of infants undergoing deferred cord clamping in comparison to immediate clamping. [ Time Frame: In the first 3 days after birth. ]A number of markers of cardiovascular status will be measured including central and peripheral capillary refill time using a PPG sensor and by the investigators observation, non-invasive blood pressure, heart rate, haemoglobin and haematocrit.
Biospecimen Retention: Samples Without DNA
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01864421
|University Hospitals Nottingham NHS Trust|
|Nottingham, Nottinghamshire, United Kingdom, NG7 2UH|
|Principal Investigator:||Don Sharkey, BMBS PhD||Univeristy of Nottingham|