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Comparison of Optic Nerve Sheath Diameter on Retrobulbar Ultrasound Before and After Drainage of Cerebrospinal Fluid in Patient With Hydrocephalus

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ClinicalTrials.gov Identifier: NCT01863329
Recruitment Status : Unknown
Verified May 2013 by Yonsei University.
Recruitment status was:  Recruiting
First Posted : May 27, 2013
Last Update Posted : May 27, 2013
Information provided by (Responsible Party):

Study Description
Brief Summary:
Studies in patients with intracranial hypertension have shown a good relationship between optic nerve sheath diameter measured by retrobulbar ultrasound and invasively measured intracranial pressure. The aim of this study was to evaluate changes in optic nerve sheath diameter before and after drainage of cerebrospinal fluid in patients with hydrocephalus.

Condition or disease Intervention/treatment
Hydrocephalus Procedure: retrobulbar ultrasound

Study Design

Study Type : Observational
Estimated Enrollment : 38 participants
Observational Model: Case-Only
Time Perspective: Prospective
Study Start Date : March 2013
Estimated Primary Completion Date : March 2014
Estimated Study Completion Date : March 2014

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Groups and Cohorts

Group/Cohort Intervention/treatment
both optic nerve sheath diameter
both optic nerve sheath diameter (the posterior 3mm of the papilla), 5 individual measurement
Procedure: retrobulbar ultrasound
both optic nerve sheath diameter (the posterior 3mm of the papilla), 5 individual measurement

Outcome Measures

Primary Outcome Measures :
  1. both optic nerve sheath diameter (the posterior 3mm of the papilla) [ Time Frame: from induction of general anesthesia to average 15 min after recovery of general anesthesia ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
patient with hydrocephalus

Inclusion Criteria:

  1. ASA Ⅰ-Ⅱ
  2. aged between 20 and 70 year
  3. hydrocephalus
  4. general anesthesia for undergoing drainage of cerebrospinal fluid

Exclusion Criteria:

1. an anatomical or functional abnormality in optic nerve

Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01863329

Contact: Hyunzu Kim, MD 82-2-2228-2422, aneshyunzu@yuhs.ac

Korea, Republic of
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine Recruiting
Seoul, Korea, Republic of, 120-752
Contact: Hyunzu Kim, MD    82-2-2228-2422    aneshyunzu@yuhs.ac   
Sponsors and Collaborators
Yonsei University
More Information

Responsible Party: Yonsei University
ClinicalTrials.gov Identifier: NCT01863329     History of Changes
Other Study ID Numbers: 4-2013-0006
First Posted: May 27, 2013    Key Record Dates
Last Update Posted: May 27, 2013
Last Verified: May 2013

Keywords provided by Yonsei University:
Optic nerve sheath diameter
Intracranial hypertension

Additional relevant MeSH terms:
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases