Effect of Lung Cancer Diagnoses on Family Behaviors
|ClinicalTrials.gov Identifier: NCT01862770|
Recruitment Status : Completed
First Posted : May 24, 2013
Last Update Posted : April 5, 2018
- A health event can be a powerful motivator for abrupt behavior changes. For instance, many people who smoke stop after having a heart attack or being diagnosed with cancer. A relative s health event may have a similar effect. For instance, smokers may try to quit after learning that a parent or sibling has lung cancer. Researchers want to study relatives of people with lung cancer to see how the relative s diagnosis affects a person s willingness to quit smoking or have genetic testing.
- To study the impact of a relative s lung cancer diagnosis on a person s approach to genetic testing and smoking cessation services.
- Current smokers between 18 and 55 years of age who are close blood relatives of people being treated for lung cancer.
- Participants will be recruited through telephone surveys. Participants will log on to a password-protected website. The site has two educational sessions and three surveys to complete.
- Participants will also be offered free genetic testing. The test will see whether they have a gene that can reduce the effectiveness of some cancer treatment drugs. Those who agree to the test will collect a cheek swab sample at home and send the sample in for testing. They will receive the test results through the website.
- The surveys will ask about risk perceptions and emotional responses to the relative s diagnosis. They will also ask about smoking history, motivation to quit, and reactions to information about smoking and genetic risk.
- All participants will be able to receive free smoking cessation services.
- Six months after completing the surveys, participants will have a follow-up phone call. The call will ask whether participants used the smoking cessation services.
|Condition or disease|
|Lung Cancer Blood Relatives of Patient w/Lung Cancer Cigarette Smokers|
|Study Type :||Observational|
|Actual Enrollment :||507 participants|
|Official Title:||Impact of a Patient's Lung Cancer Diagnosis on Relatives' Understanding of Genetic Risk Information and Receptivity to Quit Smoking|
|Study Start Date :||December 18, 2012|
|Actual Primary Completion Date :||November 25, 2013|
|Actual Study Completion Date :||February 25, 2016|
- The primary aim of the analyses is to identify for whom genetic testing for lung cancer susceptibility may be a teachable moment to promote behavior change. [ Time Frame: ongoing ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01862770
|United States, Florida|
|Moffitt Cancer Center|
|Tampa, Florida, United States, 33647|
|United States, North Carolina|
|Duke University Medical Center|
|Durham, North Carolina, United States, 27710|
|Principal Investigator:||Laura M. Koehly, Ph.D.||National Human Genome Research Institute (NHGRI)|