Muscle Strength Loss and Its Effect on Knee Cap Motion in Volunteers With Anterior Knee Pain
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|ClinicalTrials.gov Identifier: NCT01862731|
Recruitment Status : Recruiting
First Posted : May 24, 2013
Last Update Posted : January 18, 2022
- Researchers are interested in how the muscles affect the movement of the knee cap. These muscles may be related to different kinds of knee pain that are not caused by an injury or a disease. Imaging studies such as magnetic resonance imaging (MRI) can be used to look at these muscles. To study these muscles and how they move, researchers will use MRI to look at healthy individuals and individuals with knee cap pain.
- To study how changes to the muscles around the knee can influence knee pain.
- Individuals between 18 to 55 years of age who have knee cap pain that cannot be explained by a specific injury or disease.
- Healthy volunteers between 18 and 55 years of age.
- Participants will be screened with a physical exam and medical history.
- This study requires two visits. Each visit will use standard MRI sequences to take images of the knee in motion and at rest.
- On the first visit, the MRI scan will look at the knee in its natural state. Participants will move the knee up and down for 1 to 3 minutes at a time during the scan.
- On the second visit, a local anesthetic agent will be injected into the muscle of the thigh. The anesthetic will block this muscle from generating force for 2 or 3 hours. Participants will move the knee up and down for 1 to 3 minutes at a time during the MRI scan.
|Condition or disease|
|Patellofemoral Pain Syndrome|
|Study Type :||Observational|
|Estimated Enrollment :||50 participants|
|Official Title:||Vasti Control of Patellofemoral Kinematics in Patients With Chronic Patellofemoral Pain.|
|Actual Study Start Date :||May 31, 2013|
|Estimated Primary Completion Date :||December 31, 2024|
|Estimated Study Completion Date :||December 31, 2025|
2/Volunteers with Pain
Subjects with Chronic Idiopathic Patellofemoral Pain
- PF kinematics and the level of pain experience by the subject [ Time Frame: prior to and after a nerve block ]The change in patellofemoral kinematics, patellofemoral pain, and quadriceps strength pre- and post-muscle block.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01862731
|Contact: Frances Gavelli, Ph.D.||(301) firstname.lastname@example.org|
|United States, Maryland|
|National Institutes of Health Clinical Center, 9000 Rockville Pike||Recruiting|
|Bethesda, Maryland, United States, 20892|
|Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR) 800-411-1222 ext TTY8664111010 email@example.com|
|Principal Investigator:||Frances Gavelli, Ph.D.||National Institutes of Health Clinical Center (CC)|