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Trial record 1 of 1 for:    NCT01857687
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Evaluation of FFR, WSS, and TPF Using CCTA

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ClinicalTrials.gov Identifier: NCT01857687
Recruitment Status : Unknown
Verified November 2013 by Bon-Kwon Koo, Seoul National University Hospital.
Recruitment status was:  Recruiting
First Posted : May 20, 2013
Last Update Posted : November 27, 2013
Sponsor:
Information provided by (Responsible Party):
Bon-Kwon Koo, Seoul National University Hospital

Brief Summary:
To assess the feasibility of CT-derived computed fractional flow reserve (FFRCT), wall shear stress and total plaque force on coronary atherosclerotic plaque and to collect the preliminary data to apply those parameters for the prediction of clinical outcomes in patients with coronary artery stenosis.

Condition or disease
To Assess the Feasibility of CT-derived FFR, WSS and TPF on Coronary Atherosclerotic Plaque

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Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Noninvasive Evaluation of Ischemia Causing Coronary Stenosis, Wall Shear Stress, and Total Plaque Force Using Coronary CT Angiography (CCTA) and Physics-based Analytic Model Derived From Conservation of Energy
Study Start Date : May 2013
Estimated Primary Completion Date : May 2014

Group/Cohort
patients with coronary artery stenosis



Primary Outcome Measures :
  1. CT-derived computed fractional flow reserve [ Time Frame: at time of evaulation ]

Secondary Outcome Measures :
  1. wall shear stress [ Time Frame: at time of evaulation ]
  2. total plaque force [ Time Frame: at time of evaulation ]


Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
patients with coronary artery stenosis
Criteria

Inclusion Criteria:

  • Consecutive patients with available CCTA within 3 months of invasive angiography and invasive imaging methods (IVUS or OCT)

Exclusion Criteria:

  • Poor CT images (unable to reconstruct 3 dimensional coronary artery model)

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01857687


Contacts
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Contact: Bon-Kwon Koo, MD, PhD 82-2-2072-2062 bkkoo@snu.ac.kr

Locations
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Korea, Republic of
Seoul National University hospital Recruiting
Seoul, Korea, Republic of, 110744
Contact: Bon-Kwon Koo         
Seoul National University Hospital Active, not recruiting
Seoul, Korea, Republic of
Sponsors and Collaborators
Seoul National University Hospital
Publications:

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
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Responsible Party: Bon-Kwon Koo, Associate Professor of Medicine / Cardiology, Seoul National University Hospital
ClinicalTrials.gov Identifier: NCT01857687    
Other Study ID Numbers: SNUH CT-FFR WSS TPF
First Posted: May 20, 2013    Key Record Dates
Last Update Posted: November 27, 2013
Last Verified: November 2013
Additional relevant MeSH terms:
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Plaque, Atherosclerotic
Pathological Conditions, Anatomical