Working… Menu

Evaluation of FFR, WSS, and TPF Using CCTA

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01857687
Recruitment Status : Unknown
Verified November 2013 by Bon-Kwon Koo, Seoul National University Hospital.
Recruitment status was:  Recruiting
First Posted : May 20, 2013
Last Update Posted : November 27, 2013
Information provided by (Responsible Party):
Bon-Kwon Koo, Seoul National University Hospital

Brief Summary:
To assess the feasibility of CT-derived computed fractional flow reserve (FFRCT), wall shear stress and total plaque force on coronary atherosclerotic plaque and to collect the preliminary data to apply those parameters for the prediction of clinical outcomes in patients with coronary artery stenosis.

Condition or disease
To Assess the Feasibility of CT-derived FFR, WSS and TPF on Coronary Atherosclerotic Plaque

Layout table for study information
Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Noninvasive Evaluation of Ischemia Causing Coronary Stenosis, Wall Shear Stress, and Total Plaque Force Using Coronary CT Angiography (CCTA) and Physics-based Analytic Model Derived From Conservation of Energy
Study Start Date : May 2013
Estimated Primary Completion Date : May 2014

patients with coronary artery stenosis

Primary Outcome Measures :
  1. CT-derived computed fractional flow reserve [ Time Frame: at time of evaulation ]

Secondary Outcome Measures :
  1. wall shear stress [ Time Frame: at time of evaulation ]
  2. total plaque force [ Time Frame: at time of evaulation ]

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
patients with coronary artery stenosis

Inclusion Criteria:

  • Consecutive patients with available CCTA within 3 months of invasive angiography and invasive imaging methods (IVUS or OCT)

Exclusion Criteria:

  • Poor CT images (unable to reconstruct 3 dimensional coronary artery model)

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01857687

Layout table for location contacts
Contact: Bon-Kwon Koo, MD, PhD 82-2-2072-2062

Layout table for location information
Korea, Republic of
Seoul National University hospital Recruiting
Seoul, Korea, Republic of, 110744
Contact: Bon-Kwon Koo         
Seoul National University Hospital Active, not recruiting
Seoul, Korea, Republic of
Sponsors and Collaborators
Seoul National University Hospital

Publications automatically indexed to this study by Identifier (NCT Number):
Layout table for additonal information
Responsible Party: Bon-Kwon Koo, Associate Professor of Medicine / Cardiology, Seoul National University Hospital Identifier: NCT01857687    
Other Study ID Numbers: SNUH CT-FFR WSS TPF
First Posted: May 20, 2013    Key Record Dates
Last Update Posted: November 27, 2013
Last Verified: November 2013
Additional relevant MeSH terms:
Layout table for MeSH terms
Plaque, Atherosclerotic
Pathological Conditions, Anatomical