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Effectiveness and Acceptability of MoodGYM in Treating Depressive Symptoms in Chinese Americans

This study has been completed.
Information provided by (Responsible Party):
Albert Yeung, Massachusetts General Hospital Identifier:
First received: January 8, 2013
Last updated: November 30, 2016
Last verified: November 2016

This study aims to evaluate efficacy and acceptability of the Chinese language version of MoodGYM as a therapeutic intervention in treating symptoms of depression in community dwelling Chinese Americans in the Boston area.

Hypothesis 1: Participants enrolled in MoodGYM will show a significant decrease in depressive symptoms after completion of the 5 modules.

Hypothesis 2: Participants enrolled in MoodGYM will show significantly improved dysfunctional thinking.

Hypothesis 3: Participants enrolled in MoodGym will rate this program as culturally acceptable.

Condition Intervention
Major Depressive Disorder Other: MoodGYM

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Effectiveness and Acceptability of MoodGYM in Treating Depressive Symptoms in Chinese Americans

Further study details as provided by Albert Yeung, Massachusetts General Hospital:

Primary Outcome Measures:
  • Change in Center for Epidemiologic Studies Depression Scale (CES-D) [ Time Frame: Weeks 0, 6 (pre/post) ]
    The CES-D scale is a short self-report scale designed to measure depressive symptomatology in the general population. Each of the 20 items in this instrument is assigned one value of 0, 1, 2 or 3. High scores on the CES-D indicate high levels of distress.

Enrollment: 112
Study Start Date: September 2014
Study Completion Date: November 2016
Primary Completion Date: December 2015 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: MoodGYM
This study is a single-arm intervnetion. All subjects will be assigned to receive six weeks of online CBT through MoodGYM.
Other: MoodGYM
MoodGYM, a publicly-available online CBT program developed by the Centre for Mental Health Research at The Australian National University has been shown by multiple studies to be effective in reducing symptoms of depression. MoodGYM consists of five interactive modules. Participants will be asked to complete one module each week and progress through the program sequentially.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Resident of the US, but self-identified as Chinese origin
  • At least 18 years of age
  • Proficiency in Chinese, including the ability to read Chinese
  • Access to computer and internet
  • Scores > 10 on the Chinese bilingual patient health questionnaire -9 item (PHQ-9)

Exclusion Criteria:

  • Current ongoing psychiatric or psychological treatment
  • Using illicit drugs or consumption > 3 standard drinks in a day
  • Currently experiencing a psychotic illness
  • Past or current history of schizophrenia or bipolar disorder
  • ECT during the last year
  • Current active suicidal or self-injurious potential necessitating immediate face-to-face treatment
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01851967

United States, Massachusetts
Massachusetts General Hospital Depression Clinical and Research Program
Boston, Massachusetts, United States, 02114
Ying Wang
Beijing, China
Sponsors and Collaborators
Massachusetts General Hospital
  More Information

Additional Information:
Responsible Party: Albert Yeung, Principle Investigator / Psychiatrist, Massachusetts General Hospital Identifier: NCT01851967     History of Changes
Other Study ID Numbers: 2012-P-002340
Study First Received: January 8, 2013
Last Updated: November 30, 2016

Keywords provided by Albert Yeung, Massachusetts General Hospital:
Major depressive disorder
Cognitive behavioral therapy
Computerized CBT
Online CBT

Additional relevant MeSH terms:
Depressive Disorder
Depressive Disorder, Major
Mood Disorders
Mental Disorders
Behavioral Symptoms processed this record on September 21, 2017