Assessment of Coronary Artery Disease in Stroke Patients (ACADIS)
Coronary Artery Disease
|Study Type:||Observational [Patient Registry]|
|Study Design:||Observational Model: Cohort|
|Target Follow-Up Duration:||5 Years|
|Official Title:||Prevalence and Characteristics of Coronary Atherosclerosis in Stroke Patients Using Coronary CT Angiography|
- MACE (Major Adverse Cardiac Event) [ Time Frame: Participants will be followed until June. 2015, an expeded average of 5 years ] [ Designated as safety issue: No ]MACE was included as follows: 1) all-cause mortality, 2) myocardial infarction, 3) unstable angina requiring hospitalization
- Any cardiac events [ Time Frame: Participants will be followed until June. 2015, an expeded average of 5 years ] [ Designated as safety issue: No ]1) late revascularization: who underwent revascularization therapy mroe than 90days after CCTA and referral due ot new symptoms or an abnormal function test, 2) heart failure required hospitalization.
- Repeated stroke [ Time Frame: Participants will be followed until June. 2015, an expeded average of 5 years ] [ Designated as safety issue: No ]newly developed stroke after CCTA scan
|Study Start Date:||July 2006|
|Study Completion Date:||June 2015|
|Primary Completion Date:||December 2012 (Final data collection date for primary outcome measure)|
Coronary artery disease, Stroke
Coronary artery disease, stroke, coronary CT angiography
Stroke and coronary artery disease (CAD) share common risk factors and pathological mechanisms. CAD is an important cause of death in patients with stroke.
Currently, coronary CT angiography (CCTA) is very useful non-invasive tool for detection of CAD and plaque analysis.
Therefore, the investigators aimed to evaluate the prevalence, plaque characteristics (plaque types, stenosis degree, remodeling) and predictors of CAD in stroke patients through follow-up (more than 5 years) using CCTA.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01850693
|Korea, Republic of|
|Seoul National University Bundang Hospital|
|Seongnam-si, Gyeonggi-do, Korea, Republic of, 436-707|
|Principal Investigator:||Eun Ju Chun, MD||Department of Radiology, Seoul National University Bundang Hospital|