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Cardiac Functions in Living Donor Liver Transplant Recipients. An Echocardiographic Study.

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified October 2013 by Amr Mohamed Yassen, Mansoura University.
Recruitment status was:  Recruiting
Information provided by (Responsible Party):
Amr Mohamed Yassen, Mansoura University Identifier:
First received: April 23, 2013
Last updated: October 4, 2013
Last verified: October 2013
The stress of orthotopic living donor liver transplantation in patients with cirrhosis could induce worsening of an already recorded myocardial dysfunction or may be associated with a new myocardial dysfunction in patients previously having normal myocardial functions, therefore this study will be designed for intra-operative detection of new onset ventricular dysfunction or worsening of already diagnosed ventricular dysfunction in living donor liver transplant recipient and the possible contribution of several hemodynamic and oxygenation parameters in the generation of any cardiovascular function impairment will be also investigated and to determine the impact of ventricular dysfunction on early (7 PO days) graft function, 28 days survival and patient outcomes.

Liver Transplant

Study Type: Observational [Patient Registry]
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Target Follow-Up Duration: 1 Day
Official Title: Cardiac Functions in Living Donor Liver Transplant Recipients. An Echocardiographic Study.

Resource links provided by NLM:

Further study details as provided by Amr Mohamed Yassen, Mansoura University:

Primary Outcome Measures:
  • hemodynamic monitoring [ Time Frame: intraoperative ]

Secondary Outcome Measures:
  • graft function [ Time Frame: 7 days ]

Other Outcome Measures:
  • survival [ Time Frame: 28 days ]

Estimated Enrollment: 60
Study Start Date: December 2012
Estimated Study Completion Date: September 2015
Estimated Primary Completion Date: April 2015 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   20 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
recipient of living donor liver

Inclusion Criteria:

  • all adult recipient

Exclusion Criteria:

  • massive blood transfusion
  • grade III esophageal varices
  Contacts and Locations
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Please refer to this study by its identifier: NCT01840514

Contact: amr M yassen, MD +201001497044
Contact: Waleed R Elsarraf, MD +201222322727

Liver transplantation program - Gastroenterology surgical center Recruiting
Mansoura, Dakahlia, Egypt, 35511
Contact: Amr M Yassen, MD    +201001497044   
Contact: Waleed R alsarraf, MD    +201222322727   
Principal Investigator: Amr Yassen, MD         
Liver transplantation project - Gastroenterology surgical center - Mansoura university Recruiting
Mansoura, Dakahlia, Egypt, 35511
Contact: Amr M Yassen, MD    +201001497044   
Contact: Waleed R Elsarraf, MD    +201222322727   
Sub-Investigator: Amr M Yassen, MD         
Sponsors and Collaborators
Mansoura University
Principal Investigator: amr yassen, MD Liver transplant program, mansoura faculty of medicine
  More Information

Responsible Party: Amr Mohamed Yassen, professor, Mansoura University Identifier: NCT01840514     History of Changes
Other Study ID Numbers: 1982
Study First Received: April 23, 2013
Last Updated: October 4, 2013

Keywords provided by Amr Mohamed Yassen, Mansoura University:
recipient processed this record on May 25, 2017