Trial record 13 of 38 for:
Open Studies | "Pharyngitis"
Inhalation of Lidocaine Before Intubation
The recruitment status of this study is unknown because the information has not been verified recently.
Verified April 2013 by New Taipei City Hospital.
Recruitment status was Recruiting
Information provided by (Responsible Party):
Chen Yen-Po, New Taipei City Hospital
First received: April 21, 2013
Last updated: April 23, 2013
Last verified: April 2013
We investigate the potential benefits of ultrasound-driven lidocaine inhalation immediately before induction.
Drug: Lidocaine inhalation
Intervention Model: Single Group Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Prevention
||The Effect of Ultrasonic Nebulizer Delivered Lidocaine on Circulatory Responses During Tracheal Intubation and Postoperative Sore Throat
Primary Outcome Measures:
Secondary Outcome Measures:
| Estimated Enrollment:
| Study Start Date:
| Estimated Primary Completion Date:
||May 2013 (Final data collection date for primary outcome measure)
Active Comparator: Lidocaine
Inhalation of lidocaine before intubation
Drug: Lidocaine inhalation
Lidocaine inhalation before intubation
Placebo Comparator: Control
Normal saline inhalation before intubation
Sudden increases in blood pressure and heart rate after tracheal intubation and post-operative sore throat are two common undesirable side effects of general anesthesia and might lead to patients' morbidity or dissatisfaction. We investigated the possibility to attenuate both side effects with one single method, i.e. ultrasound-driven lidocaine inhalation immediately before induction.
|Ages Eligible for Study:
||20 Years to 65 Years
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
- American Society of Anesthesiologists (ASA) physical status I or II. Patients scheduled for elective surgery under general anesthesia with orotracheal intubation
- patient's refusal to join, major surgery or expected operation duration longer than 3 hours, patients with a anticipated difficult airway, requiring a nasogastric tube in peri-operative stage, having recent upper respiratory tract infection (within 1 week) or pre-existing sore throat.
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01838993
|New Taipei City Hospital
|New Taipei City, Taiwan |
|Contact: Lin Chi-Hsuan, MD email@example.com |
New Taipei City Hospital
||Chen Yen Po, MD
||New Taipei City Hospital
No publications provided
||Chen Yen-Po, Physician, New Taipei City Hospital
History of Changes
|Other Study ID Numbers:
|Study First Received:
||April 21, 2013
||April 23, 2013
||Taiwan: Department of Health
Keywords provided by New Taipei City Hospital:
nebulizers and vaporizers;
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on August 27, 2015
Respiratory Tract Diseases
Respiratory Tract Infections
Central Nervous System Agents
Central Nervous System Depressants
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Peripheral Nervous System Agents
Physiological Effects of Drugs
Sensory System Agents
Sodium Channel Blockers
Voltage-Gated Sodium Channel Blockers