Non-invasive and Invasive Plaque Characterisation
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|ClinicalTrials.gov Identifier: NCT01833338|
Recruitment Status : Terminated (The study was terminated based on an included stopping rule in the study protocol)
First Posted : April 16, 2013
Last Update Posted : September 11, 2014
|Condition or disease||Intervention/treatment||Phase|
|Non ST Elevation Myocardial Infarction||Device: Imaging||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||30 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Coronary Artery Plaque Characterisation With Non-invasive Multi-Slice Computed Tomography and Invasive Intravascular Ultrasound and Optical Coherence Tomography in Patients With Acute Coronary Syndromes Without ST-segment Elevation|
|Study Start Date :||June 2011|
|Actual Primary Completion Date :||May 2013|
|Actual Study Completion Date :||May 2013|
There is only one arm in this study. All patients undergo MSCT, IVUS and OCT.
All patients undergo non-invasive (MSCT) and invasive (IVUS, OCT) imaging
- Accuracy of detection of thrombus with MSCT as compared to IVUS and OCT will be investigated. [ Time Frame: 24 hours ]All imaging methods will be performed in each patient. A 24 hour period is the maximum allowed time gap between MSCT and invasive imaging (OCT/IVUS).
- Accuracy of atherosclerotic plaque characterisation with MSCT as compared to IVUS and OCT will be investigated. [ Time Frame: 24 hours ]A maximum interval of 24 hours between MSCT and IVUS/OCT is allowed in this study.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01833338
|University Medical Center Groningen, Departments of Cardiology and Radiology|
|Groningen, Netherlands, 9700 RB|
|Principal Investigator:||Gabija Pundziute, MD, PhD||Department of Cardiology|
|Principal Investigator:||Tineke Willems, MD, PhD||Department of Radiology|