Non-invasive and Invasive Plaque Characterisation
|ClinicalTrials.gov Identifier: NCT01833338|
Recruitment Status : Terminated (The study was terminated based on an included stopping rule in the study protocol)
First Posted : April 16, 2013
Last Update Posted : September 11, 2014
|Condition or disease||Intervention/treatment||Phase|
|Non ST Elevation Myocardial Infarction||Device: Imaging||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||30 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Coronary Artery Plaque Characterisation With Non-invasive Multi-Slice Computed Tomography and Invasive Intravascular Ultrasound and Optical Coherence Tomography in Patients With Acute Coronary Syndromes Without ST-segment Elevation|
|Study Start Date :||June 2011|
|Actual Primary Completion Date :||May 2013|
|Actual Study Completion Date :||May 2013|
There is only one arm in this study. All patients undergo MSCT, IVUS and OCT.
All patients undergo non-invasive (MSCT) and invasive (IVUS, OCT) imaging
- Accuracy of detection of thrombus with MSCT as compared to IVUS and OCT will be investigated. [ Time Frame: 24 hours ]All imaging methods will be performed in each patient. A 24 hour period is the maximum allowed time gap between MSCT and invasive imaging (OCT/IVUS).
- Accuracy of atherosclerotic plaque characterisation with MSCT as compared to IVUS and OCT will be investigated. [ Time Frame: 24 hours ]A maximum interval of 24 hours between MSCT and IVUS/OCT is allowed in this study.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01833338
|University Medical Center Groningen, Departments of Cardiology and Radiology|
|Groningen, Netherlands, 9700 RB|
|Principal Investigator:||Gabija Pundziute, MD, PhD||Department of Cardiology|
|Principal Investigator:||Tineke Willems, MD, PhD||Department of Radiology|