This site became the new on June 19th. Learn more.
Show more Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu
Give us feedback

Adiponectin and Ethnic Differences in Insulin Resistance

This study has been completed.
Information provided by (Responsible Party):
University of Colorado, Denver Identifier:
First received: April 5, 2013
Last updated: April 9, 2013
Last verified: April 2013
The purpose of this protocol is to measure and compare levels of the circulating protein adiponectin and adiponectin's association with insulin sensitivity in Mexican Americans and non-Latino white subjects. The investigators also aimed to examine associations between nutritional factors and adiponectin levels.

Condition Intervention
Insulin Resistance Type 2 Diabetes Other: none- observational study

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Adiponectin as an Independent Determinant of Ethnic Differences in Insulin Resistance

Resource links provided by NLM:

Further study details as provided by University of Colorado, Denver:

Primary Outcome Measures:
  • total adiponectin concentration [ Time Frame: measured once during second study visit, in fasting condition ]

Secondary Outcome Measures:
  • Insulin sensitivity [ Time Frame: Measured once, during second study visit. ]
    Calculated from insulin and glucose values obtained during IV glucose tolerance test.

Enrollment: 43
Study Start Date: March 2011
Study Completion Date: August 2011
Primary Completion Date: August 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
non-Latino white
no Latino ancestry, Caucasian
Other: none- observational study
Mexican American
Mexican American ancestry
Other: none- observational study


Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Community sample

Inclusion Criteria:

  • 18-60 years of age
  • BMI 20.0-34.9 m/kg2
  • Mexican American with at least 3 grandparents born in Mexico or white with no grandparents of Latino descent.

Exclusion Criteria:

  • pregnancy
  • breastfeeding
  • diabetes mellitus
  • blood pressure > 160/100 mmHg
  • creatinine > 1.5 mg/dl or glomerular filtration rate (GFR) < 60
  • liver function tests > 3x upper limit of normal (ULN)
  • h/o heart failure
  • h/o eating disorder
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01831102

United States, Colorado
University of Colorado Anschutz Medical Center
Aurora, Colorado, United States, 80045
Sponsors and Collaborators
University of Colorado, Denver
Principal Investigator: Rocio Pereira, MD University of Colorado, Denver
  More Information

Responsible Party: University of Colorado, Denver Identifier: NCT01831102     History of Changes
Other Study ID Numbers: 10-1260
Study First Received: April 5, 2013
Last Updated: April 9, 2013

Keywords provided by University of Colorado, Denver:
insulin resistance
ethnic disparities

Additional relevant MeSH terms:
Insulin Resistance
Glucose Metabolism Disorders
Metabolic Diseases
Hypoglycemic Agents
Physiological Effects of Drugs processed this record on September 25, 2017