Physiological Response of Cortisol to Cardiac Catheterization
Cortisol is essential for survival. The importance of cortisol response is most apparent in patients with partial or complete deficiency of glucocorticoids during stressful events such as illness or surgery.
|Study Design:||Observational Model: Case-Crossover
Time Perspective: Cross-Sectional
|Official Title:||Physiological Response of Cortisol to Cardiac Catheterization|
- cortisol change [ Time Frame: one month ] [ Designated as safety issue: No ]On the day of the procedure a total of 4 venous blood samples for random plasma cortisol level will be obtained. Blood will be drawn at 5 minutes prior to the procedure, at 30 minutes and 60 minutes during the cardiac catheterization. Another sample will be drawn in 3 hours after cardiac catheterization prior to the patients discharge. a cortisol level will be drawn at a "nonstressful" visit
|Study Start Date:||March 2013|
|Study Completion Date:||April 2014|
|Primary Completion Date:||April 2014 (Final data collection date for primary outcome measure)|
patients undergoing elective heart catheterization
It is known that cortisol and other stress hormones increase during acute myocardial infarction as well (9-11). Cardiac catheterization is an essential tool for the management of acute coronary syndrome, and for the evaluation of the burden of coronary artery disease in cardiac patients.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01822847
|United States, Nebraska|
|Omaha, Nebraska, United States, 68131|
|Principal Investigator:||Valentina Tarasova, MD||Creighton University|