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Testing Hypersensitivity to Metals in Sarcoidosis Patients by Applying the MELISA Test.

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified March 2013 by Tel-Aviv Sourasky Medical Center.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT01809145
First Posted: March 12, 2013
Last Update Posted: March 12, 2013
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Tel-Aviv Sourasky Medical Center
  Purpose
The purpose of this study is to apply the MELISA test, that diagnose hypersensitivity to metals, in Sarcoidosis patients with occupational exposure.

Condition Intervention
Sarcoidosis Other: MELISA test

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Official Title: Testing Hypersensitivity to Metals in Sarcoidosis Patients With Occupational Exposure, Using the MELISA Test.

Resource links provided by NLM:


Further study details as provided by Tel-Aviv Sourasky Medical Center:

Primary Outcome Measures:
  • MELISA test [ Time Frame: 30 days ]
    Using the MELISA test in peripheral blood, in order to find hypersensitivity to metals that can be related to the granulomatous response of sarcoidosis.


Estimated Enrollment: 10
Study Start Date: March 2013
Estimated Study Completion Date: December 2013
Estimated Primary Completion Date: December 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
metal hypersensitivity
peripheral blood test for metal hypersensitivity (MELISA test)
Other: MELISA test
MELISA test for hypersensitivity to metals in sarcoidosis

Detailed Description:
Peripheral blood from sarcoidosis patients with occupational anamnesis that involves exposure to metals will be sent to MELISA Medica in Stockholm Sweden. The MELISA test will examine hypersensitivity to metals that can be related to the granulomatous response of sarcoidosis.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

Biopsy confirmed sarcoidosis Granulomatous disease Occupational anamnesis with exposure to metals

Exclusion Criteria:

Patients with interstitial disease No occupational anamnesis

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01809145


Contacts
Contact: Elizabeth Fireman, PhD 972-36973988 fireman@tlvmc.gov.il

Locations
Israel
Tel-Aviv Sourasky Medical Center Recruiting
Tel Aviv, Israel, 64239
Contact: Elizabeth Fireman, PhD    972-36973988    fireman@tlvmc.gov.il   
Contact: Yifat Alcalay, PhD    973-36973749    yifatal@tlvmc.gov.il   
Sponsors and Collaborators
Tel-Aviv Sourasky Medical Center
Investigators
Principal Investigator: Elizabeth Fireman, PhD Tel-Aviv Sourasky Medical Center
  More Information

Responsible Party: Tel-Aviv Sourasky Medical Center
ClinicalTrials.gov Identifier: NCT01809145     History of Changes
Other Study ID Numbers: TASMC-13-LF-0683-CTIL
First Submitted: March 7, 2013
First Posted: March 12, 2013
Last Update Posted: March 12, 2013
Last Verified: March 2013

Keywords provided by Tel-Aviv Sourasky Medical Center:
sarcoidosis
occupational exposure
MELISA

Additional relevant MeSH terms:
Hypersensitivity
Sarcoidosis
Immune System Diseases
Lymphoproliferative Disorders
Lymphatic Diseases