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Prehospital Cerebral Oxygenation During Cardiopulmonary Resuscitation (CPR)

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ClinicalTrials.gov Identifier: NCT01806844
Recruitment Status : Completed
First Posted : March 7, 2013
Last Update Posted : April 21, 2016
Ziekenhuis Oost-Limburg
Information provided by (Responsible Party):
Cornelia Genbrugge, Hasselt University

Brief Summary:
Near infrared spectroscopy (NIRS) is a technique that measures regional cerebral oxygenation in a non-invasive manner. Through the use of near infrared light, the difference between oxygenated and deoxygenated hemoglobin can be measured. By applying the Beer-Lamber law, a numeric result can be calculated. During a cardiac arrest, there is no stroke volume, no cardiac output and no cerebral perfusion. By using cerebral NIRS during out-of hospital cardiac arrest, low flow time and return of spontaneous circulation, this study wants to show the prognostic value of NIRS as extra monitoring.

Condition or disease
Cardiac Arrest

Study Type : Observational
Actual Enrollment : 200 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Cerebral Oxygenation During Resuscitation and Post-resuscitation Phase
Study Start Date : May 2013
Primary Completion Date : November 2015
Study Completion Date : November 2015

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Cardiac Arrest
U.S. FDA Resources

Primary Outcome Measures :
  1. prognostic value [ Time Frame: 1 year ]
    Prognostic value of cerebral oxygenation during CPR

Information from the National Library of Medicine

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Ages Eligible for Study:   16 Years and older   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
pre-hospital cardiac arrest

Inclusion Criteria:

  • >16 year

Exclusion Criteria:

  • DNR code

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01806844

Ziekenhuis Oost-Limburg
Genk, Limburg, Belgium, 3600
Universitair ziekenhuis Leuven
Leuven, Vlaams Brabant, Belgium, 3000
Ziekenhuis netwerk Antwerpen
Antwerpen, Belgium, 2000
GZA St Vincentius
Antwerp, Belgium
AZ Turnhout
Turnhout, Belgium
Sponsors and Collaborators
Hasselt University
Ziekenhuis Oost-Limburg
Principal Investigator: Cornelia Genbrugge, MD Hasselt University

Responsible Party: Cornelia Genbrugge, Dr. Genbrugge, Hasselt University
ClinicalTrials.gov Identifier: NCT01806844     History of Changes
Other Study ID Numbers: Copernicus I
First Posted: March 7, 2013    Key Record Dates
Last Update Posted: April 21, 2016
Last Verified: April 2016

Keywords provided by Cornelia Genbrugge, Hasselt University:
Cardiac arrest
Cerebral oxygenation

Additional relevant MeSH terms:
Heart Arrest
Heart Diseases
Cardiovascular Diseases