Efficacy and Safety of Biocellulose Sheet Containing Anti-hyperpigmentation Agent ("Biocellulose Mask", "Farhorm®") in Patients Receiving Laser Treatment
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT01806831
Recruitment Status :
First Posted : March 7, 2013
Last Update Posted : March 11, 2015
Agricultural Research Development Agency (Public Organization)
Information provided by (Responsible Party):
Pornanong Aramwit, Pharm.D., Ph.D, Chulalongkorn University
The laser areas treated with biocellulose sheet from coconut juice containing anti-hyperpigmentation agent ("biocellulose mask", "Farhorm®") heal faster than vaseline ointment which is a standard treatment.
Condition or disease
Skin PigmentationSkin Irritation
Device: "Biocellulose Mask", Farhorm®"
Volar surface at upper arm (2X2 cm) on both sides were treated with semi ablative, 1,550 nm Erbium: glass fractional laser. Biocellulose sheet from coconut juice containing anti-hyperpigmentation agent ("biocellulose mask","Farhorm®")was applied for 20 min on one side and the other side was treated with vaseline ointment. The redness, skin hydration and skin pigmentation were evaluated at that area before laser, immediately after laser and after applying the treatment. These parameters were compared between treatment (area treated with Biocellulose sheet from coconut juice containing anti-hyperpigmentation agent, "biocellulose mask", "Farhorm®") and control (vaseline ointment).
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study:
20 Years to 50 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Age 20-50 years old
No skin problem such as inflammation, fresh wounds
Not receive laser treatment during last 3 months
No history of smoking or alcohol drinking
No allergy to licorice extract, Vit C, Vit E, arbutin or stearyl glycyrrhetinate
Willing to participate in this study and can comply with study protocol
Has history of hyperallergic reaction
Has wound(s) on face during last 4 weeks
Has history of eczema, psoriasis during last 6 months
Has laser treatment during last month
Use steroid, antibiotic, anti-inflammatory drugs or antihistamine during 3 days before recruiting