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Evaluation of Antihypertensive Drugs in OSA Patients (ADOSA)

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01803815
First Posted: March 4, 2013
Last Update Posted: November 3, 2014
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Universidade Nova de Lisboa
  Purpose
This prospective cohort study aimed to assess the phenotypic characteristics of OSA patients and their pattern of antihypertensive drugs consumption. The investigators also aimed to investigate a hypothetical association between ongoing anti-hypertensive regimen and Blood pressure control rates in these patients. Additionally, the investigators were also interested in trying to understand if the control of OSA may be influenced by the use of different classes of anti-hypertensive drugs.

Condition
Hypertension Obstructive Sleep Apnea

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Evaluation of Antihypertensive Drugs in Patients With Obstructive Sleep Apnea

Resource links provided by NLM:


Further study details as provided by Universidade Nova de Lisboa:

Primary Outcome Measures:
  • Number of participants with uncontrolled BP before CPAP (Continuous Positive Airway Pressure) adaptation. [ Time Frame: patients will be followed up for an expected average time of 2 months ]

Enrollment: 369
Study Start Date: April 2010
Study Completion Date: April 2013
Primary Completion Date: February 2013 (Final data collection date for primary outcome measure)
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Consecutive patients, male and women, aged above 18 years, that attended a first visit at CHLN Hospital Sleep Unit, located in Lisbon, were enrolled.
Criteria

Inclusion Criteria:

  • aged above 18 years, that attended a first visit at CHLN Hospital Sleep Unit were enrolled

Exclusion Criteria:

  • severe psychiatric disease or inability to understand the information required for an informed consent.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01803815


Locations
Portugal
Universidade Nova de Lisboa - Faculdade de Ciências Médicas
Lisboa, Portugal, 1169-056
Sponsors and Collaborators
Universidade Nova de Lisboa
Investigators
Principal Investigator: Lucilia N Diogo, PharmD, MSc Universidade Nova de Lisboa - CEDOC
Study Chair: Paula Pinto, PhD, MD CHLN
Study Chair: Cristina Bárbara, PhD, MD CHLN
Study Director: Emilia C Monteiro, PhD, MD Universidade Nova de Lisboa
Study Director: Ana L Papoila, PhD Universidade Nova de Lisboa
  More Information

Additional Information:
Responsible Party: Universidade Nova de Lisboa
ClinicalTrials.gov Identifier: NCT01803815     History of Changes
Other Study ID Numbers: NOVA - CEDOC/FCT
First Submitted: February 27, 2013
First Posted: March 4, 2013
Last Update Posted: November 3, 2014
Last Verified: October 2014

Keywords provided by Universidade Nova de Lisboa:
obstructive sleep apnea
hypertension
antihypertensive drugs

Additional relevant MeSH terms:
Hypertension
Apnea
Sleep Apnea Syndromes
Sleep Apnea, Obstructive
Vascular Diseases
Cardiovascular Diseases
Respiration Disorders
Respiratory Tract Diseases
Signs and Symptoms, Respiratory
Signs and Symptoms
Sleep Disorders, Intrinsic
Dyssomnias
Sleep Wake Disorders
Nervous System Diseases
Antihypertensive Agents