Evaluation of Antihypertensive Drugs in OSA Patients (ADOSA)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01803815
Recruitment Status : Completed
First Posted : March 4, 2013
Last Update Posted : November 3, 2014
Information provided by (Responsible Party):
Universidade Nova de Lisboa

Brief Summary:
This prospective cohort study aimed to assess the phenotypic characteristics of OSA patients and their pattern of antihypertensive drugs consumption. The investigators also aimed to investigate a hypothetical association between ongoing anti-hypertensive regimen and Blood pressure control rates in these patients. Additionally, the investigators were also interested in trying to understand if the control of OSA may be influenced by the use of different classes of anti-hypertensive drugs.

Condition or disease
Hypertension Obstructive Sleep Apnea

Study Type : Observational
Actual Enrollment : 369 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Evaluation of Antihypertensive Drugs in Patients With Obstructive Sleep Apnea
Study Start Date : April 2010
Actual Primary Completion Date : February 2013
Actual Study Completion Date : April 2013

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Primary Outcome Measures :
  1. Number of participants with uncontrolled BP before CPAP (Continuous Positive Airway Pressure) adaptation. [ Time Frame: patients will be followed up for an expected average time of 2 months ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Consecutive patients, male and women, aged above 18 years, that attended a first visit at CHLN Hospital Sleep Unit, located in Lisbon, were enrolled.

Inclusion Criteria:

  • aged above 18 years, that attended a first visit at CHLN Hospital Sleep Unit were enrolled

Exclusion Criteria:

  • severe psychiatric disease or inability to understand the information required for an informed consent.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01803815

Universidade Nova de Lisboa - Faculdade de Ciências Médicas
Lisboa, Portugal, 1169-056
Sponsors and Collaborators
Universidade Nova de Lisboa
Principal Investigator: Lucilia N Diogo, PharmD, MSc Universidade Nova de Lisboa - CEDOC
Study Chair: Paula Pinto, PhD, MD CHLN
Study Chair: Cristina Bárbara, PhD, MD CHLN
Study Director: Emilia C Monteiro, PhD, MD Universidade Nova de Lisboa
Study Director: Ana L Papoila, PhD Universidade Nova de Lisboa

Additional Information:
Responsible Party: Universidade Nova de Lisboa Identifier: NCT01803815     History of Changes
Other Study ID Numbers: NOVA - CEDOC/FCT
First Posted: March 4, 2013    Key Record Dates
Last Update Posted: November 3, 2014
Last Verified: October 2014

Keywords provided by Universidade Nova de Lisboa:
obstructive sleep apnea
antihypertensive drugs

Additional relevant MeSH terms:
Sleep Apnea Syndromes
Sleep Apnea, Obstructive
Vascular Diseases
Cardiovascular Diseases
Respiration Disorders
Respiratory Tract Diseases
Signs and Symptoms, Respiratory
Signs and Symptoms
Sleep Disorders, Intrinsic
Sleep Wake Disorders
Nervous System Diseases
Antihypertensive Agents