The Prognostic Assessment of Extubation in Aged Patients With Multiple Organ Dysfunction Syndrome
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ClinicalTrials.gov Identifier: NCT01802983
Recruitment Status : Unknown
Verified February 2013 by Kun Xiao, Chinese PLA General Hospital. Recruitment status was: Recruiting
The multiple organ dysfunction syndrome (MODS) has remained the major factor contributing to prolongation of intensive and mortality. It is reported that the mortality rates have varied between 20% and 100%, depending on number, severity, duration, type and combination, and definition of dysfunction. In our study, the investigators explore some comprehensive treatment technology to improved outcomes of MODS patients.
the prognostic assessment of aged patients with MODS [ Time Frame: 28 days ]
According to the outcomes of 28-day,all the enrolled patients were divided into survival group and death group, clinical datum of which were collected and analysed. And then these prognosis were evaluated with the current scoring systems [(Acute Physiology and Chronic Health EvaluationⅡ(APACHEⅡ, APACHE Ⅲ), Sample Acute Physiological score(SAPSⅡ), Multiple Organ Dysfunction score(MODS)], the predictive power of which were compared by receiver operating characteristic(ROC) curve. Finally, a binary logistic regression analysis was performed to evaluate the concerning prognostic factors of MODSE.
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Ages Eligible for Study:
60 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
All subjects were selected from among inpatients who were hospitalized between Jan 2009 and May 2013 in the Respiratory Intensive Care Unit(RICU),Surgical Intensive Care Unit(SICU) and Emergency Intensive Care Unit(EICU).
age > 60 years old;
presence of altered organ function in an acutely ill patient such that homeostasis cannot be maintained without intervention;
have trachea intubation after admitting to intensive care unit within 24 hours.