Electrophysiologic HV-interval as a Predicor for Permanent Pacemaker Implantation After TAVI
|ClinicalTrials.gov Identifier: NCT01801098|
Recruitment Status : Completed
First Posted : February 28, 2013
Last Update Posted : November 13, 2013
The development of a high grade AV-block is a frequent complication associated with transcatheter aortic valve implantation (TAVI). Patients who were suitable for TAVI will be enrolled in this study. The HV-interval will be determined before and immediately after implantation.
The hypothesis is that a prolonged HV-interval is associated with a high rate of complete AV-block following TAVI.
|Condition or disease|
|Symptomatic Aortic Valve Stenosis|
|Study Type :||Observational|
|Actual Enrollment :||25 participants|
|Official Title:||Electrophysiologic HV-interval as a Predicor for Permanent Pacemaker Implantation After Transcatheter Aortic Valve Implantation With a Self-expanding Bioprosthesis|
|Study Start Date :||December 2012|
|Primary Completion Date :||November 2013|
|Study Completion Date :||November 2013|
- Determination of HV interval [ Time Frame: Changes in Baseline to 24 hours ]HV-interval will be determined by a 5F quadripolar electrode catheter with a CRD-2 curve configuration. Intracardiac signals will be assessed and determined before and after implantation.
- AV-block development after 1 month, 6 months and 12 months [ Time Frame: 1 month, 6 months and 12 months ]
- cardiovascular mortality [ Time Frame: 1 month, 6 months and 12 months ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01801098
|Division of Cardiology, Pulmonary Diseases, Vascular Medicine, University Hospital Duesseldorf|
|Duesseldorf, NRW, Germany, 40225|
|Principal Investigator:||Malte Kelm, MD||Division of Cardiology, Pulmonary Diseases, Vascular Medicine, University Hospital Duesseldorf|
|Principal Investigator:||Marc W. Merx, MD||Division of Cardiology, Pulmonary Diseases, Vascular Medicine University Hospital Duesseldorf|
|Principal Investigator:||Dong-In Shin, MD||Division of Cardiology, Pulmonary Diseases, Vascular Medicine, University Hospital Duesseldorf|