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ClinicalTrials.gov Identifier: NCT01792427
: February 15, 2013
Last Update Posted
: February 20, 2013
Universitaire Ziekenhuizen Leuven
Information provided by (Responsible Party):
Dr. Lieven Dupont, Universitaire Ziekenhuizen Leuven
In this study we analyzed the overall survival for all newly diagnosed patients with non-cystic fibrosis bronchiectasis from June 2006 onwards. The investigators wanted to confirm the known risk factors such as age, gender, smoking history and Pseudomonas aeruginosa and evaluate the impact on survival of etiology, number of different bacteriological species in retrospective and prospective sputa, azithromycin use and presence/development of pulmonary hypertension.
risk factor identification for NCFB [ Time Frame: 6 years 4 months ]
The investigators wanted to confirm the known risk factors such as age, gender, smoking history and Pseudomonas aeruginosa.
Other Outcome Measures:
Identify cause of death [ Time Frame: 6 years 4 months ]
If death occurred, the patient file was reassessed to identify cause of death.
risk factor identification for the survival of NCFB [ Time Frame: 6 years 4 months ]
The investigators will evaluate the impact of etiology, number of different bacteriological species in retrospective and prospective sputa, azithromycin use and presence/development of pulmonary hypertension on survival .
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Ages Eligible for Study:
18 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
non-cystic fibrosis bronchiectasis
Patients with clinically significant and radiologically proven bronchiectasis
Chest CT scan confirming the presence of bronchiectatic lesions and had symptoms of chronic productive cough
Bronchiectasis was deemed to be present if there was one or more of the following criteria: a bronchoarterial ratio greater than 1, lack of tapering of the bronchi and visualization of bronchi within 1 cm of costal or paravertebral pleura or abutting the mediastinal pleura
diagnosis of cystic fibrosis
underlying tumoral problem causing the bronchiectatic lesions (postradiotherapy, secondary immunodeficiency due to chemotherapy or postinfectious due to tumoral obstruction)
patients with asymptomatic traction bronchiectasis caused by interstitial lung disease