Antispastic Effect of Transcranial Magnetic Stimulation in Patients With Cerebral and Spinal Spasticity (ANTMS)

Inclusion Criteria:

The age of the patients and healthy volunteers from 18 to 70 years

• persons with confirmed and verified lesion of the central nervous system (the effects of CVD, multiple sclerosis, traumatic brain injury, SMC) with symptoms of spasticity any vyrazhenngosti;
• informed consent;
• healthy volunteers who gave informed consent to participate in the study.

The criteria included:

• The presence of an implanted pacemaker, intracardiac catheters, electronic pumps;
• The difficult patient, requiring the maintenance of vital functions by hardware (mechanical ventilation, continuous application infusomats), including an increase of neurological symptoms after 8 days from the start of CVD, acute myocardial infarction, venous thrombosis of the lower extremities, episodes of pulmonary embolism;
• The severity of the neurological deficit, which does not allow the patient to go through 10 meters (you can use an additional support);
• Pregnancy or possibility of pregnancy in women of childbearing age (before menopause), according to a pregnancy test;
• The presence of metal implants or in the head area, located closer than 20 cm from the edge of the surface coil magnetic stimulator, with the exception of the mouth (metal brackets, vascular sutures, metal plate covering defects in the skull, metallic foreign body in the cavity of the skull);
• Identification of epileptiform activity during the screening EEG prior to the study;
• Epilepsy or seizures in history;
• Failure of a patient to participate in the study;

Exclusion Criteria:

• Identification of the study a total intolerance to a pulsed magnetic field;

  • Development after inclusion of acute myocardial infarction and acute ischemic;
  • Installation of the pacemaker, intracardiac catheters or operations on the brain, requiring the abandonment of metal objects in the cranial cavity;
  • Pregnancy;
  • Enhancement of the patient, which requires the maintenance of vital functions by hardware (mechanical ventilation, continuous application infusomats);
  • The emergence of an epileptic seizure in response to rhythmic TMS;
  • Failure of the patient to continue participation in the study;