CPAP/PSV Preoxygenation in Obese Patients

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01780571
Recruitment Status : Completed
First Posted : January 31, 2013
Last Update Posted : January 31, 2013
Information provided by (Responsible Party):
Erik Näslund, Karolinska Institutet

Brief Summary:
The purpose of this study is to determine whether continuouse positive airway pressure (CPAP), during induction of anaesthesia in morbidly obese patients, result in higher levels of oxygen in the blood.

Condition or disease Intervention/treatment Phase
Obesity Anaesthesia Procedure: CPAP 5 cm H2O + PSV 5 cm H2O Not Applicable

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 44 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Prevention
Official Title: Continuous Positive Airway Pressure/Pressure Support Preoxygenation of Morbidly Obese Patients
Study Start Date : May 2009
Actual Primary Completion Date : June 2012
Actual Study Completion Date : December 2012

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Anesthesia
U.S. FDA Resources

Arm Intervention/treatment
No Intervention: Control group
Neutral pressure breathing after 2 min preoxygenation
Active Comparator: Active group
CPAP 5cm H2O + PSV 5cm H2O breathing after 2 min preoxygenation
Procedure: CPAP 5 cm H2O + PSV 5 cm H2O
Patients in the intervention group received Continuous Positive Airway Pressure (5 cm H2O) and Pressure Supported Ventilation (5 cm H2O)

Primary Outcome Measures :
  1. Post intubation PaO2levels [ Time Frame: 5 minutes after intubation ]
    PaO2 levels is measured within 5 minutes after the completion of intubation.

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • body mass index (BMI) > 35 kg/m2
  • scheduled to undergo elective gastric bypass surgery
  • age ≥ 18 years
  • ASA Physical Status Classification II-III

Exclusion Criteria:

  • significant cardiopulmonary disease
  • previous abdominal or thoracic surgery
  • inability to comprehend the protocol.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01780571

Department of Anesthesiology and Intensive Care Danderyd Hospital
Stockholm, Sweden, 18288
Sponsors and Collaborators
Karolinska Institutet

Responsible Party: Erik Näslund, Professor, Karolinska Institutet Identifier: NCT01780571     History of Changes
Other Study ID Numbers: KIDS CPAP
First Posted: January 31, 2013    Key Record Dates
Last Update Posted: January 31, 2013
Last Verified: January 2013

Keywords provided by Erik Näslund, Karolinska Institutet:
general anaesthesia