We updated the design of this site on September 25th. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

CPAP/PSV Preoxygenation in Obese Patients

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01780571
First Posted: January 31, 2013
Last Update Posted: January 31, 2013
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Erik Näslund, Karolinska Institutet
  Purpose
The purpose of this study is to determine whether continuouse positive airway pressure (CPAP), during induction of anaesthesia in morbidly obese patients, result in higher levels of oxygen in the blood.

Condition Intervention
Obesity Anaesthesia Procedure: CPAP 5 cm H2O + PSV 5 cm H2O

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Prevention
Official Title: Continuous Positive Airway Pressure/Pressure Support Preoxygenation of Morbidly Obese Patients

Resource links provided by NLM:


Further study details as provided by Erik Näslund, Karolinska Institutet:

Primary Outcome Measures:
  • Post intubation PaO2levels [ Time Frame: 5 minutes after intubation ]
    PaO2 levels is measured within 5 minutes after the completion of intubation.


Enrollment: 44
Study Start Date: May 2009
Study Completion Date: December 2012
Primary Completion Date: June 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
No Intervention: Control group
Neutral pressure breathing after 2 min preoxygenation
Active Comparator: Active group
CPAP 5cm H2O + PSV 5cm H2O breathing after 2 min preoxygenation
Procedure: CPAP 5 cm H2O + PSV 5 cm H2O
Patients in the intervention group received Continuous Positive Airway Pressure (5 cm H2O) and Pressure Supported Ventilation (5 cm H2O)

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • body mass index (BMI) > 35 kg/m2
  • scheduled to undergo elective gastric bypass surgery
  • age ≥ 18 years
  • ASA Physical Status Classification II-III

Exclusion Criteria:

  • significant cardiopulmonary disease
  • previous abdominal or thoracic surgery
  • inability to comprehend the protocol.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01780571


Locations
Sweden
Department of Anesthesiology and Intensive Care Danderyd Hospital
Stockholm, Sweden, 18288
Sponsors and Collaborators
Karolinska Institutet
  More Information

Responsible Party: Erik Näslund, Professor, Karolinska Institutet
ClinicalTrials.gov Identifier: NCT01780571     History of Changes
Other Study ID Numbers: KIDS CPAP
First Submitted: December 9, 2012
First Posted: January 31, 2013
Last Update Posted: January 31, 2013
Last Verified: January 2013

Keywords provided by Erik Näslund, Karolinska Institutet:
Obesity
general anaesthesia
preoxygenation
atelectasis