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This study has been completed.
Information provided by (Responsible Party):
Didem Arslan Tas, Cukurova University Identifier:
First received: January 29, 2013
Last updated: NA
Last verified: January 2011
History: No changes posted
Background: Genetics is suggested to play a critical role in the development of Behçet's disease (BD). Shared phenotypic features requires an approach to the differential diagnosis from periodic febrile syndromes particularly from mevalonate kinase deficiency related diseases. We planned to study for evaluating the frequency of mutations and their clinical significance in mevalonate kinase gene in Turkish patients with Behçet's disease.

Behçet's Disease

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by Didem Arslan Tas, Cukurova University:

Primary Outcome Measures:
  • Frequency of mevalonate kinase frequency in Behçet disease [ Time Frame: One year ]

Secondary Outcome Measures:
  • Mevalonate kinase gene and clinical correlations in Behçet's disease [ Time Frame: One year ]

Study Start Date: January 2011
Primary Completion Date: December 2011 (Final data collection date for primary outcome measure)
frequency of mevalonate kinase gene frequency
Behçet patients
frequency of mevalonate kinase gene mutations


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Turkish kindred

Inclusion Criteria:

  • Behçet patients

Exclusion Criteria:

  • Diagnosis of periodic fever syndromes
  Contacts and Locations
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Please refer to this study by its identifier: NCT01780363

Cukurova University
Adana, Turkey, 01330
Didem Arslan Tas
Adana, Turkey, 01330
Sponsors and Collaborators
Cukurova University
  More Information

Responsible Party: Didem Arslan Tas, MD, Cukurova University Identifier: NCT01780363     History of Changes
Other Study ID Numbers: BH-MVK
CUTFBAP25011138 ( Other Identifier: CUTF )
CUTFBAP2501201138 ( Other Identifier: CUTFBAP )
Study First Received: January 29, 2013
Last Updated: January 29, 2013

Additional relevant MeSH terms:
Behcet Syndrome
Mouth Diseases
Stomatognathic Diseases
Uveal Diseases
Eye Diseases
Vascular Diseases
Cardiovascular Diseases
Hereditary Autoinflammatory Diseases
Genetic Diseases, Inborn
Skin Diseases, Genetic
Skin Diseases
Skin Diseases, Vascular
Uveitis, Anterior
Vasculitis processed this record on September 21, 2017