Calf Muscle Atrophy After Achilles Tendon Rupture. A Clinical-Radiological-Biomechanical Multicenter Study.

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01778816
Recruitment Status : Completed
First Posted : January 29, 2013
Last Update Posted : January 29, 2013
Hospital Fribourg, Switzerland
Hospital Liestal, Switzerland
Information provided by (Responsible Party):
Claudio Rosso, University Hospital, Basel, Switzerland

Brief Summary:

Multicenter Achilles tendon study Switzerland. Comparing three mainstream treatment types: open, percutaneous and conservative (non-operative) treatments.

Comparing force torque measurements, muscle volume and clinical scores.

Condition or disease
Achilles Tendon Ruptures

Study Type : Observational
Actual Enrollment : 52 participants
Observational Model: Cohort
Time Perspective: Retrospective
Study Start Date : January 2009
Actual Primary Completion Date : July 2009
Actual Study Completion Date : December 2011

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Tears
U.S. FDA Resources

Primary Outcome Measures :
  1. Muscle Volume [ Time Frame: at least 3 years after injury ]

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
  • Age 20-65 years
  • BMI < 40
  • no injury to leg
  • no injury on contralateral leg

Inclusion Criteria:

  • 20-65 years of age,
  • a healthy, contralateral leg
  • physiological, clinically determined alignment of the knee, foot and ankle
  • no trauma to the healthy leg
  • no neuromuscular impairments including muscle dystrophies
  • no other posttraumatic injuries or osteoarthritis of the knee, foot or ankle of the affected leg.

Exclusion Criteria:

  • re-rupture or reoperation of the Achilles tendon
  • surgical site infection
  • neuromuscular diseases including muscle dystrophies
  • ankle valgus of more than 15° or ankle varus of more than 5°
  • other known pathologies of the non-affected leg
  • general MRI exclusion criteria (e.g. pacemaker, other metal not qualifying for an MRI, tattoos and claustrophobia)
  • body mass index (BMI) of > 40 kg/m2

Responsible Party: Claudio Rosso, Claudio Rosso MD MSc, University Hospital, Basel, Switzerland Identifier: NCT01778816     History of Changes
Other Study ID Numbers: RossoAchilles
First Posted: January 29, 2013    Key Record Dates
Last Update Posted: January 29, 2013
Last Verified: January 2013

Keywords provided by Claudio Rosso, University Hospital, Basel, Switzerland:
Achilles tendon, muscle volume, Achilles tendon length, force, ATRS, Hannover, AOFAS

Additional relevant MeSH terms:
Wounds and Injuries