Efficacy and Safety of Mate Extracts on Decrement of Body and Abdominal Fat in Obese Subjects
|Obesity||Dietary Supplement: Mate extract Dietary Supplement: Placebo||Phase 2|
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Prevention
|Official Title:||Mate Extract Supplementation Reduces Body and Abdominal Fat in Obese Korean Subjects|
- Changes in body and abdominal fat [ Time Frame: body fat: baseline, 6 weeks and 12 weeks, abdominal fat of CT: baseline and 12 weeks ]
- Changes in anthropometric parameters(weight, BMI, waist and hip circumference) [ Time Frame: baseline, 6 weeks and 12 weeks ]
- Changes in blood lipid profile(total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol, free fatty acid) [ Time Frame: baseline, 6 weeks and 12 weeks ]
|Study Start Date:||October 2011|
|Study Completion Date:||March 2012|
|Primary Completion Date:||February 2012 (Final data collection date for primary outcome measure)|
Experimental: Mate extracts group
Mate extract(3150 mg/day)for 12 weeks
Dietary Supplement: Mate extract
Mate is a South American herb that is traditionally prepared as a tea and used, among others, for weight reduction.
Other Name: Extracts of Ilex paraguariensis A. St.-Hil.
Placebo Comparator: Placebo group
Placebo (3150 mg/day) for 12 weeks
Dietary Supplement: Placebo
Amount and calorie of placebo are same with Mate extracts.
The primary aim of the study was to investigate the effect of Mate extracts in Korean subjects on body fat and abdominal fat, double blind, placebo-controlled clinical trial.
Thirty obesity subjects with BMI ≥ 25 kg/㎡ and waist-hip ratio (WHR)≥ 0.90 for men and ≥ 0.85 for women were for 12 weeks.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01778257
|Principal Investigator:||Min-Gul Kim, MD||Chonbuk National University Hospital|