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Effects of High Protein Intake With Intense Exercise and Energy Deficit (RIPPED)

This study has been completed.
Information provided by (Responsible Party):
Stuart M. Phillips, McMaster University Identifier:
First received: January 14, 2013
Last updated: June 6, 2015
Last verified: June 2015
A four week intervention will take place with the participants. They will undergo 6 days a week of high intensity training. They will also be at a 40% energy deficiency. One group will have a normal intake of protein, 1.2g/kg, while the other will have 2.4g/kg. It is our thesis that the participants with the higher protein will retain more lean mass.

Condition Intervention
Overweight Dietary Supplement: High Protein Dietary Supplement: Low Protein

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Basic Science
Official Title: Effects of High Protein Intake With Intense Exercise and Energy Deficit

Resource links provided by NLM:

Further study details as provided by Stuart M. Phillips, McMaster University:

Primary Outcome Measures:
  • Body Composition [ Time Frame: 4 weeks ]
    To compare the effect of normal protein intake (1.2 g/kg per day) and increased protein intake (2.4 g/kg per day) on body composition over a 4 week period of energy restriction in young males (18-30), with intense exercise training. Body composition will be measured via DXA, Bod Pod, Bio-impedance, skin folds.

Secondary Outcome Measures:
  • Psychological state [ Time Frame: 4 weeks ]
    To compare the psychological state of the participants, before, during and after the intervention. To see if the mind will grow with the body as high intensity exercise is performed, or whether the mind will tire and scores will be reduced. Measurement tactics will in include POMS, and PANAS questionnaires for mood, and stroop, isometric hand grip, operation span test, and vigilance task.

Enrollment: 40
Study Start Date: February 2013
Study Completion Date: December 2014
Primary Completion Date: July 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: High Protein
High Protein
Dietary Supplement: High Protein
2.4g/kg of protein
Placebo Comparator: Low Protein
Low Protein
Dietary Supplement: Low Protein
1.2g/kg of protein


Ages Eligible for Study:   18 Years to 30 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • 18-30 males
  • Healthy

Exclusion Criteria:

  • more than 15% body fat
  • 35-50ml/kg/min VO2
  • BMI grater than 27
  Contacts and Locations
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Please refer to this study by its identifier: NCT01776359

Canada, Ontario
McMaster University
Hamilton, Ontario, Canada, L8S 4L8
Sponsors and Collaborators
McMaster University
Principal Investigator: Stuart M Phillips, PhD McMaster University