Molecular Epidemiology of Lung Adenocarcinoma in Multi-ethnic Asian Phenotype
Recruitment status was: Recruiting
Other: Characterise the molecular epidemiology of lung adenocarcinoma in multi-ethnic asian phenotypes
|Study Design:||Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Diagnostic
|Official Title:||Molecular Epidemiology of Lung Adenocarcinoma in Multi-ethnic Asian Phenotype|
- Descriptive study of our patients with lung adenocarcinoma. Identify novel molecular characteristics so that potential drug development can be reached. [ Time Frame: 6 years ]
|Study Start Date:||December 2010|
|Estimated Study Completion Date:||December 2016|
|Estimated Primary Completion Date:||December 2016 (Final data collection date for primary outcome measure)|
Lung cancer is a malignant disease of heterogeneous histology and is divided into 2 major groups; small cell lung cancer and non-small cell lung cancer (NSCLC). NSCLC accounts for 75% of lung cancers, and can exhibit different pathways of resistance during treatment. It is increasingly apparent that effective treatment of NSCLC will require multiple drugs that attack different targets. This realization sets the stage for future individualized therapies that will depend on the molecular characteristics of NSCLC to target various pathways.
- Describe the molecular epidemiology of lung adenocarcinoma in multi-ethnic asian phenotype.
- Correlate tumor molecular characteristics with patient demographics and outcome to better understand carcinogenesis as well as in the discovery of novel targets for future drug development.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01774526
|National University Hospital/ National University of Singapore|
|Principal Investigator:||Pyng Lee, MD||National University Hospital, Singapore|