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Reliability of Cardiac Output Monitoring Based on Uncalibrated Pulse Contour Analysis

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified January 2013 by Northern State Medical University.
Recruitment status was:  Recruiting
Information provided by (Responsible Party):
Northern State Medical University Identifier:
First received: January 15, 2013
Last updated: January 18, 2013
Last verified: January 2013
The aim of our study was to evaluate the reliability of uncalibrated cardiac index monitoring based on arterial waveform analysis in patients undergoing off-pump coronary artery bypass grafting.

Cardiac Index

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Evaluation of Reliability of Cardiac Output Monitoring Based on Uncalibrated Pulse Contour Analysis During Off-pump Coronary Artery Bypass Grafting

Resource links provided by NLM:

Further study details as provided by Northern State Medical University:

Primary Outcome Measures:
  • Validity of cardiac index measurement [ Time Frame: Up to 24 hrs post surgery ]
    Accuracy and precision of cardiac index measurement using uncalibrated pulse contour analysis in comparison with transpulmonary thermodilution

Biospecimen Retention:   None Retained
No biospecimens are to be retained.

Estimated Enrollment: 40
Study Start Date: October 2011
Estimated Study Completion Date: March 2013
Estimated Primary Completion Date: March 2013 (Final data collection date for primary outcome measure)
Detailed Description:
Using contemporary statistical method the cardiac index values obtained via uncalibrated pulse contour analysis with Pro AQT system will be compared with traditional transpulmonary thermodilution technique (Pulsion, Germany).

Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with coronary artery disease, ranked ASA II-III and scheduled for elective off-pump coronary artery bypass grafting

Inclusion Criteria:

  • elective off-pump coronary artery bypass grafting

Exclusion Criteria:

  • age < 18 and > 80 years,
  • preoperative ejection fraction < 0.35,
  • severe cardiac valve dysfunction or peripheral vascular disease,
  • constant atrial fibrillation,
  • simultaneous interventions (carotid endarterectomy, aneurysm repair, etc.),
  • transfer to cardiopulmonary bypass.
  Contacts and Locations
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Please refer to this study by its identifier: NCT01773720

Contact: Mikhail Y Kirov, MD, PhD +7-8182-63-27-30

Russian Federation
Dep. of Anesthesiology, Northern SMU Recruiting
Arkhangelsk, Russian Federation, 163000
Contact: Mikhail Y Kirov, MD, PhD    +7-8182-63-27-30   
Principal Investigator: Alexey A Smetkin, MD         
Sub-Investigator: Mikhail Y Kirov, MD, PhD         
Sub-Investigator: Ayyaz Hussain, MD         
Sub-Investigator: Vsevolod V Kuzkov, MD, PhD         
Sub-Investigator: Lars J Bjertnæs, MD, PhD         
Sponsors and Collaborators
Northern State Medical University
Study Director: Mikhail Y Kirov, MD, PhD Northern State Medical Univercity
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Northern State Medical University Identifier: NCT01773720     History of Changes
Other Study ID Numbers: UncalPCA-vs-TPTD
Study First Received: January 15, 2013
Last Updated: January 18, 2013

Keywords provided by Northern State Medical University:
cardiac index
coronary artery bypass
uncalibrated pulse contour analysis
hemodynamic monitoring processed this record on April 27, 2017