Measurement of Retinal Venous Pressure Under Short-term Low-oxygen Environment
The hypothesis is that the pressure in the retinal veins increases under a short-term lack of oxygen and leads to a decreased blood circulation. On the basis of measurements in the hypobaric chamber this hypothesis should be verified.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Measurement of Retinal Venous Pressure (Retinal Venous Pressure RVP) Under Conditions of Reduced Ambient Pressure and Oxygen Partial Pressure|
- Retinal venous pressure [ Time Frame: 1 hour ] [ Designated as safety issue: No ]Quantify the changes in the retinal venous pressure (RVP)
|Study Start Date:||December 2011|
|Study Completion Date:||July 2014|
|Primary Completion Date:||May 2014 (Final data collection date for primary outcome measure)|
Conduct a pilot study to describe and quantify the retinal venous pressure (RVP) in healthy volunteers under conditions of controlled, reduced ambient and oxygen partial pressure in the pressure chamber of the Aeromedical Institute FAI in Dübendorf, Switzerland. Obtaining evidence of the adaptation behavior of the retinal vascular system in controlled, short-term hypoxic changes.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01771757
|University of Basel, Dept. of Ophthalmology|
|Basel, Switzerland, 4031|
|Study Director:||Josef Flammer, MD||University of Basel, Dept. of Ophthalmology|