Pilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy
The purpose of this pilot study is to employ multiphoton microscopy to non-invasively image in-vivo pigmented and non-pigmented human skin for characterization of their morphologic and functional features. Currently, there is no standard non-invasive method for skin imaging.
|Study Design:||Observational Model: Case-Only
Time Perspective: Retrospective
|Official Title:||Non-invasive Skin Imaging Using Multiphoton Microscopy|
- non-cancer skin [ Time Frame: up to 12 months ] [ Designated as safety issue: No ]Multiphoton microscopy imaging to collect information about changes in skin cells and tissue
|Study Start Date:||April 2012|
|Estimated Study Completion Date:||June 2018|
|Estimated Primary Completion Date:||June 2018 (Final data collection date for primary outcome measure)|
Multiphoton microscopy imaging to collect information about changes in skin cells and tissue
Device: multiphoton microscopy.
Researchers developed non-invasive imaging modalities a multiphoton tomograph image human skin. The researchers can identify the differences between pigmented and non-pigmented skin areas, such as the presence benign and cancerous skin lesions can be imaged and evaluated using the multiphoton microscopy device imaging method without standard of care skin biopsy surgical procedure.
The skin excision will be performed by the health care provider under standard of care procedure, the microscopy images data obtained before excision from the same area will be compared with histopathology report to identify eventual changes in cellular morphology.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01771718
|Contact: Montana Compton, RNfirstname.lastname@example.org|
|Contact: Mihaela Balu, PhD|
|United States, California|
|Beckman Laser Institute Medical Clinic||Recruiting|
|Irvine, California, United States, 92612|
|Contact: Montana Compton, RN 949-824-9265 email@example.com|
|Principal Investigator: Kristen Kelly, MD|
|Sub-Investigator: Mihaela Balu, PhD|
|Sub-Investigator: Montana Compton, RN|
|Sub-Investigator: Christopher Zachary, MD|
|Sub-Investigator: Tatiana Krasieva, PhD|
|Sub-Investigator: Ataollah Sharif, MD|
|Sub-Investigator: Viera Crosignani, PhD|
|Sub-Investigator: Rolf Saager, PhD|
|Principal Investigator:||Kristen Kelly, MD||Beckman Laser Institute, UCI|