We are updating the design of this site. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Psychophysical Aspects of Maximal Anaerobic Performance

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified January 2013 by Hillel Yaffe Medical Center.
Recruitment status was:  Not yet recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT01770288
First Posted: January 17, 2013
Last Update Posted: January 17, 2013
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborators:
University of Haifa
Zinman College of Physical Education and Sports Sciences
Information provided by (Responsible Party):
Hillel Yaffe Medical Center
  Purpose

During anaerobic exercise, the metabolic pathway of glycolysis is used in order to produces high-energy compounds adenosine triphosphate (ATP).The level of lactic acid in the blood is a marker to the increased protons concentration and acidosis.nevertheless, the increased level of protons in addition to the release of bradykinin causes pain during the exercise that limited the subject's performance. Therefore, it is assumed that the individual pain sensitivity might determine the subject's performance.

Aims: To investigate the role of the DNIC efficiency in prediction of anaerobic performance in humans (2) to study the role of peripheral pro-nociceptive processing in mediating pain during anaerobic exercise and its contribution to the subjects' performance (3) to assess the function of pain-related psychological factors in anaerobic performance.


Condition Intervention
Anaerobic Performance Other: Anaerobic wingate test

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Screening
Official Title: Psychophysical Aspects of Maximal Anaerobic Performance

Further study details as provided by Hillel Yaffe Medical Center:

Primary Outcome Measures:
  • Pain psychophysics tests [ Time Frame: 1 year ]
    DNIC will be tested using a paradigm of two remote noxious stimuli with one, the 'conditioning stimulus' (immersing the hand in tub containing 8°c water), inhibiting the other, the 'test pain' (pressure pain threshold) in order to assess the EA efficiency (2) heat and pressure pain thresholds, and (3) temporal summation of painful heat and mechanical stimuli that reflect the neuroplasticity of the central nervous system following peripheral noxious stimulation.


Secondary Outcome Measures:
  • Lactate concentration [ Time Frame: 1 year ]
    Lactate concentration at rest will be measures using a portable lactate analyzer

  • The anaerobic performance [ Time Frame: 1 year ]
    will be evaluated during executing of Wingate test


Estimated Enrollment: 40
Study Start Date: February 2013
Estimated Study Completion Date: April 2013
Estimated Primary Completion Date: February 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Anaerobic Performance Other: Anaerobic wingate test

Detailed Description:

To the best of our knowledge, no study has investigated the balance between the endogenous anti-nociceptive properties of the individual and the anaerobic-evoke pro-nociceptive activity in determining the maximal performance during anaerobic exercise. Moreover, the interaction between psychological factors and pro- and anti- nociceptive processes that are operated during anaerobic exercise, need to be investigated.

Methods: Forty healthy men and women, between the ages of 18-40 will be involved in the study. Each participant will complete 3 psychological questionnaires regarding their personality traits: Pain Catastrophizing Scale (PCS), State-Trait Anxiety Inventory and Perceived Stress Questionnaire. Pain psychophysics tests will be used for evaluating the individual pain perception, prior and subsequent to the anaerobic exercise: (1) DNIC will be tested using a paradigm of two remote noxious stimuli with one, the 'conditioning stimulus' (immersing the hand in tub containing 8°c water), inhibiting the other, the 'test pain' (pressure pain threshold) in order to assess the endogenous analgesia (EA) efficiency (2) heat and pressure pain thresholds, and (3) temporal summation of painful heat and mechanical stimuli that reflect the neuroplasticity of the central nervous system following peripheral noxious stimulation. In addition, Anaerobic performance will be evaluated during Wingate test,and blood lactate will be measured. Gene related pain ill be tested using saliva samples .

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 40 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

healthy Volunteers

Exclusion Criteria:

pregnancy

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01770288


Contacts
Contact: Einat Kodesh, PhD ekodesh@univ.haifa.ac.il

Locations
Israel
Zinman College for Physical Education and Sport Sciences at the Wingate Institute Not yet recruiting
Netanya, Israel, 42902
Contact: Yoav Mekel, PhD         
Sub-Investigator: Irit Weisman-Fogel, PhD         
Principal Investigator: Yoav Mekel, PhD         
Sponsors and Collaborators
Hillel Yaffe Medical Center
University of Haifa
Zinman College of Physical Education and Sports Sciences
Investigators
Principal Investigator: Einat Kodesh, PhD University of Haifa
  More Information

Responsible Party: Hillel Yaffe Medical Center
ClinicalTrials.gov Identifier: NCT01770288     History of Changes
Other Study ID Numbers: 8-12
First Submitted: January 6, 2013
First Posted: January 17, 2013
Last Update Posted: January 17, 2013
Last Verified: January 2013

Keywords provided by Hillel Yaffe Medical Center:
Anerobic exercise
Pain
Analgesia
Diffuse Noxious Inhibitory Control (DNIC)
psychological stress