Study to Test the Value of a Pain Modulation Test in Predicting Persistent Postoperative Pain After Breast Cancer Surgery (PREDO)

This study is ongoing, but not recruiting participants.
Information provided by (Responsible Party):
Benno Rehberg-Klug, University Hospital, Geneva Identifier:
First received: January 10, 2013
Last updated: May 1, 2015
Last verified: May 2015

The purpose of this study is to test the hypothesis that a preoperative test of pain modulation predicts persistent pain 4 months after breast cancer surgery.

Chronic Pain
Acute Pain

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Trial of Diagnostic Accuracy for the Prediction of Persistent Postoperative Pain After Breast Cancer Surgery Using a Conditioned Pain Modulation Test

Resource links provided by NLM:

Further study details as provided by University Hospital, Geneva:

Primary Outcome Measures:
  • prevalence of pain at the site of surgery [ Time Frame: 4 months postop ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

venous blood sample

Estimated Enrollment: 180
Study Start Date: May 2011
Estimated Study Completion Date: May 2016
Primary Completion Date: April 2015 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

women scheduled for any type of breast cancer surgery in a university hospital breast cancer center


Inclusion Criteria:

  • age >=18 years
  • American Society of Anesthesiology functional status I-III
  • able to read and understand the information sheet and give informed consent

Exclusion Criteria:


  Contacts and Locations
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Please refer to this study by its identifier: NCT01767168

Hôpitaux Universitaires de Genève
Geneva, Switzerland, 1211
Sponsors and Collaborators
University Hospital, Geneva
Principal Investigator: Benno Rehberg-Klug, MD Dept of Anesthesiology, HUG
  More Information

No publications provided

Responsible Party: Benno Rehberg-Klug, médecin adjoint agrégé, University Hospital, Geneva Identifier: NCT01767168     History of Changes
Other Study ID Numbers: CER 10-218, matped 10-054
Study First Received: January 10, 2013
Last Updated: May 1, 2015
Health Authority: Switzerland: Ethikkommission

Additional relevant MeSH terms:
Acute Pain
Chronic Pain
Pain, Postoperative
Nervous System Diseases
Neurologic Manifestations
Pathologic Processes
Postoperative Complications
Signs and Symptoms processed this record on July 30, 2015