This site became the new on June 19th. Learn more.
Show more Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu
Give us feedback

The Influence of Oxytocin on Automatic Imitation Behaviour in Healthy Adults

This study has been completed.
Research Foundation Flanders
Information provided by (Responsible Party):
University Ghent Identifier:
First received: January 10, 2013
Last updated: January 16, 2013
Last verified: January 2013
In this study, the influence of oxytocin on automatic imitation behaviour is investigated. Healthy adults will be administered with either oxytocin or a placebo, and will perform an imitation-inhibition task (as a measure of automatic imitation behaviour). To determine the specificity of the oxytocin effect, an unrelated cognitive task (Stroop task) will also be presented.

Condition Intervention Phase
Healthy Drug: Oxytocin Drug: Sea water Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Basic Science

Resource links provided by NLM:

Further study details as provided by University Ghent:

Primary Outcome Measures:
  • To evaluate the automatic imitation behaviour 45 minutes after drug administration [ Time Frame: 120 minutes ]
    Since the effects of oxytocin are only visible after 45 minutes, participants will have to wait 45 minutes before starting the experimental tasks. In the meantime, they will be given an unrelated cognitive-emotional filler task which will last ± 30 minutes. Afterwards, they will perform two experimental tasks: an imitation-inhibition task and a cognitive control task (Stroop task).

Enrollment: 60
Study Start Date: November 2012
Study Completion Date: December 2012
Primary Completion Date: December 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Oxytocin
Oxytocin 24 IU (3 puffs) per nostril
Drug: Oxytocin
Placebo Comparator: Sea water
Sea water 3 puffs per nostril
Drug: Sea water


Ages Eligible for Study:   18 Years to 40 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Male
  • non-smoker

Exclusion Criteria:

  • no pacemaker, deep brain stimulation electrodes or other stimulation devices
  • normal neurological history (no brain operations, migraine, epilepsy, alcoholism
  • no epilepsy in family
  • no chronic disease(s) that require constant medication (asthma, hypertension, diabetes)
  • no medication 24h prior to experiment
  • no alcohol or caffeine 2h prior to experiment
  • no sleep deprivation 24h prior to experiment
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01767025

Ghent University, Faculty of Psychology and Educational Sciences
Ghent, Belgium, 9000
Sponsors and Collaborators
University Ghent
Research Foundation Flanders
Principal Investigator: Guy T'Sjoen, MD, PhD Ghent University, Faculty of Endrocrinology
  More Information

Responsible Party: University Ghent Identifier: NCT01767025     History of Changes
Other Study ID Numbers: 2012/550
Study First Received: January 10, 2013
Last Updated: January 16, 2013

Keywords provided by University Ghent:
automatic imitation

Additional relevant MeSH terms:
Reproductive Control Agents
Physiological Effects of Drugs processed this record on August 21, 2017