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The Influence of Oxytocin on Automatic Imitation Behaviour in Healthy Adults

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ClinicalTrials.gov Identifier: NCT01767025
Recruitment Status : Completed
First Posted : January 11, 2013
Last Update Posted : January 17, 2013
Sponsor:
Collaborator:
Research Foundation Flanders
Information provided by (Responsible Party):
University Ghent

Brief Summary:
In this study, the influence of oxytocin on automatic imitation behaviour is investigated. Healthy adults will be administered with either oxytocin or a placebo, and will perform an imitation-inhibition task (as a measure of automatic imitation behaviour). To determine the specificity of the oxytocin effect, an unrelated cognitive task (Stroop task) will also be presented.

Condition or disease Intervention/treatment Phase
Healthy Drug: Oxytocin Drug: Sea water Phase 3

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 60 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Basic Science
Study Start Date : November 2012
Primary Completion Date : December 2012
Study Completion Date : December 2012

Resource links provided by the National Library of Medicine

Drug Information available for: Oxytocin
U.S. FDA Resources

Arm Intervention/treatment
Experimental: Oxytocin
Oxytocin 24 IU (3 puffs) per nostril
Drug: Oxytocin
Placebo Comparator: Sea water
Sea water 3 puffs per nostril
Drug: Sea water



Primary Outcome Measures :
  1. To evaluate the automatic imitation behaviour 45 minutes after drug administration [ Time Frame: 120 minutes ]
    Since the effects of oxytocin are only visible after 45 minutes, participants will have to wait 45 minutes before starting the experimental tasks. In the meantime, they will be given an unrelated cognitive-emotional filler task which will last ± 30 minutes. Afterwards, they will perform two experimental tasks: an imitation-inhibition task and a cognitive control task (Stroop task).



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 40 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Male
  • non-smoker

Exclusion Criteria:

  • no pacemaker, deep brain stimulation electrodes or other stimulation devices
  • normal neurological history (no brain operations, migraine, epilepsy, alcoholism
  • no epilepsy in family
  • no chronic disease(s) that require constant medication (asthma, hypertension, diabetes)
  • no medication 24h prior to experiment
  • no alcohol or caffeine 2h prior to experiment
  • no sleep deprivation 24h prior to experiment

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01767025


Locations
Belgium
Ghent University, Faculty of Psychology and Educational Sciences
Ghent, Belgium, 9000
Sponsors and Collaborators
University Ghent
Research Foundation Flanders
Investigators
Principal Investigator: Guy T'Sjoen, MD, PhD Ghent University, Faculty of Endrocrinology

Responsible Party: University Ghent
ClinicalTrials.gov Identifier: NCT01767025     History of Changes
Other Study ID Numbers: 2012/550
First Posted: January 11, 2013    Key Record Dates
Last Update Posted: January 17, 2013
Last Verified: January 2013

Keywords provided by University Ghent:
Influence
oxytocin
automatic imitation
behaviour
volunteers

Additional relevant MeSH terms:
Oxytocin
Oxytocics
Reproductive Control Agents
Physiological Effects of Drugs