Evaluating Treatment Efficacy of Two Syntactic Treatment Procedures for Children With Specific Language Impairment (SLI): A Randomized Controlled Trial
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|ClinicalTrials.gov Identifier: NCT01765348|
Recruitment Status : Completed
First Posted : January 10, 2013
Last Update Posted : January 10, 2013
Specific-language-impairment (SLI) is defined as a significant disorder in language development, which affects one's daily functioning, but not attributable to sensory, intellectual or neuropsychological deficit. Children with SLI make up one of the largest subgroups of students with special educational needs (SEN) in Hong Kong. Without appropriate intervention, SLI may persist into adolescence and lead to long-term literacy difficulties and social rejection, which were found to be associated with societal problems like unemployment and crime commitment. Among the language domains, syntax/grammar has been viewed as a core deficit in these children. Speech-Language-Pathologists (SLPs) often provide intervention on this aspect for them. However, very few intervention efficacy studies could be identified.
Without pertinent research evidence, clinical-decision-making in treatment approach selection may be dubious. This study aims to evaluate the efficacy of two procedures for syntax intervention, namely the Sentence-Combining (SC) and Narrative-Based (NAR) procedures using a randomized-controlled-trial (RCT) design. These two procedures have been indicated to be effective in previous case reports and expert opinions. By using the rigorous study design of RCT, this study provides stronger evidence to support clinicians in determining the most effective treatment procedure. To achieve sufficient statistical power to detect the treatment difference, 52 children with SLI will be recruited and randomly assigned to one of the treatment groups. The primary outcome will be measured by a standardized language assessment. Intention-to-treat analysis will be employed. Pre- and post-treatment scores on the outcomes will be subject to analyses of covariance with the pre-treatment scores as the covariate.
|Condition or disease||Intervention/treatment||Phase|
|Language Impairment in School-years||Behavioral: Syntax treatment via sentence-combining method Behavioral: Syntax treatment managed by narrative-based treatment||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||52 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Outcomes Assessor)|
|Official Title:||Evaluating Treatment Efficacy of Two Syntactic Treatment Procedures for Children With Specific Language Impairment (SLI): A Randomized Controlled Trial|
|Study Start Date :||March 2012|
|Actual Primary Completion Date :||August 2012|
|Actual Study Completion Date :||December 2012|
|Experimental: Sentence combining||
Behavioral: Syntax treatment via sentence-combining method
Sentence combining method is a discrete trial method that teaches children to form complex sentences of a same structure through drilling and modeling.
Treatments are conduced by school-speech therapist once two weeks for 8 sessions.
|Active Comparator: Narrative based method||
Behavioral: Syntax treatment managed by narrative-based treatment
Target structures are embedded into narrative stories. Children are exposed to these stories and are scaffolded to form the target sentence structure through answering questions, cloze passage and story retell. Treatment are conduced by school-speech therapist once two weeks for 8 sessions.
- Changes from baseline in language scores based on a standardized language assessment [ Time Frame: Children were followed up to 6 months ]All the children were followed for about 6 months in the middle of the school year when they received regular therapy from their school speech-therapists. Children's language skills were assessed by research speech therapists using a standardized language assessment pre and post treatment.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01765348
|Carol K. S. TO|
|Hong Kong, HK, Hong Kong, HK|
|Principal Investigator:||Carol K. S. To, PhD||The University of Hong Kong|