Khalifa Acute Effects
The primary hypothesis is that Khalifa's therapy has different acute effects in various organ systems i.e. proprioceptive, neuro-muscular, endogenous dopamine system, etc. These effects might indicate the pathway of the therapy.
Totally Ruptured Anterior Cruciate Ligament in the Knee
Other: Khalifa Therapy
|Study Design:||Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Basic Science
|Official Title:||Interdisciplinary Evaluation of Acute Effects From Khalifa's Therapy at Patients With Fully Ruptured Anterior Cruciate Ligament (ACL).|
- Laser Doppler-Flow [ Time Frame: 1 hour ] [ Designated as safety issue: No ]Perfusion
- NIRS [ Time Frame: 1 hour ] [ Designated as safety issue: No ]Near infrared spectroscopy, Oxygen saturation
- IR Thermography [ Time Frame: 1 hour ] [ Designated as safety issue: No ]Infrared thermography, temperature
- QST [ Time Frame: 1 hour ] [ Designated as safety issue: No ]Quantitative sensoric testing, pain
- HRV [ Time Frame: 1 hour ] [ Designated as safety issue: No ]Heart rate variability, sympathicus/parasympathicus activation
- EEG [ Time Frame: 1 hour ] [ Designated as safety issue: No ]Electroencephalogram, brain waves
- Knee function [ Time Frame: 1 hour ] [ Designated as safety issue: No ]IKDC Score KT-1000 test Clinical / physical examination
- SportsScience [ Time Frame: 2 hours ] [ Designated as safety issue: No ]Posturomed Motion capture proprioception muscle power range of motion
- Blood [ Time Frame: 1 hour ] [ Designated as safety issue: No ]Catecholamines endorphins standard blood parameters
- Questionnaire [ Time Frame: 1 hour ] [ Designated as safety issue: No ]Different questions about pain, lifestyle, subjective parameters
|Study Start Date:||December 2012|
|Estimated Study Completion Date:||May 2013|
|Estimated Primary Completion Date:||January 2013 (Final data collection date for primary outcome measure)|
Getting one time one hour of Khalifa's therapy for ACL injury treatment.
Other: Khalifa Therapy
One hour of Khalifa's therapy which is specially applied pressure to the skin.
According to our previous study that evaluated the efficacy of Khalifa's therapy the investigators have seen that the therapy has acute effects which resulted in better knee function and later even in better healing of the ACL injury. This study should clear exactly which effects and pathways are involved in the therapy from multiple (interdisciplinary) point of views. Therefore the investigators will measure parameters that might be associated with this special technique directly before and after the therapy.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01762371
|Sports Center of University Salzburg|
|Hallein, Salzburg, Austria, 5400|
|Principal Investigator:||Andreas Kastner, MD||AKH Linz|
|Principal Investigator:||Andreas Sandner, MD||Med Uni Graz|