Chronic Myelod Leukemia Registry at Asan Medical Center
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ClinicalTrials.gov Identifier: NCT01761695 |
Recruitment Status :
Terminated
(The PI resigned the institute. The rest investigators at the institute decided to terminate the study.)
First Posted : January 7, 2013
Last Update Posted : July 20, 2018
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Condition or disease | Intervention/treatment |
---|---|
Leukemia, Chronic Myeloid Myeloid Leukemia, Chronic, Accelerated Phase Myeloid Leukemia, Chronic, Chronic Phase | Other: Diagnosed as CML |
- Acquisition of informed concent form
-
Data acquisition from medical record including
- demographic / disease-associated factors
- details of treatment, and its results
- complications during treatment
- genetic data
- survival outcome (upto 30 years)
- Accumulation of data for 30 years
- Use of data for other retrospective analysis (including Asan Medical center Cell Banking basic data)
Study Type : | Observational [Patient Registry] |
Actual Enrollment : | 100 participants |
Observational Model: | Cohort |
Time Perspective: | Prospective |
Target Follow-Up Duration: | 30 Years |
Official Title: | Prospective Observational Cohort Registry for Patients With Chronic Myeloid Leukemia at Asan Medical Center |
Study Start Date : | January 2013 |
Actual Primary Completion Date : | May 2016 |
Actual Study Completion Date : | May 2016 |

Group/Cohort | Intervention/treatment |
---|---|
CML CP
Diagnosed as CML with chronic phase
|
Other: Diagnosed as CML
All patients who will be enrolled in this prospective registry are confined to those who are diagnosed as chronic myeloid leukemia at Asan Medical Center, Seoul, Korea, from Jan 2013 till Dec 2047
Other Name: Diagnosed as chronic myeloid leukemia |
CML AP
Diagnosed as CML with accelerated phase
|
Other: Diagnosed as CML
All patients who will be enrolled in this prospective registry are confined to those who are diagnosed as chronic myeloid leukemia at Asan Medical Center, Seoul, Korea, from Jan 2013 till Dec 2047
Other Name: Diagnosed as chronic myeloid leukemia |
CML BC
Diagnosed as CML with blast crisis
|
Other: Diagnosed as CML
All patients who will be enrolled in this prospective registry are confined to those who are diagnosed as chronic myeloid leukemia at Asan Medical Center, Seoul, Korea, from Jan 2013 till Dec 2047
Other Name: Diagnosed as chronic myeloid leukemia |
CML other
Diagnosed as CML, which is not included in any of other category
|
Other: Diagnosed as CML
All patients who will be enrolled in this prospective registry are confined to those who are diagnosed as chronic myeloid leukemia at Asan Medical Center, Seoul, Korea, from Jan 2013 till Dec 2047
Other Name: Diagnosed as chronic myeloid leukemia |
- Overall survival [ Time Frame: 30 years ]
- Event-free survival [ Time Frame: 30 years ]Definition of events will be as 'failure', 'progress to AP/BC', 'intolerant and medication change', and 'death from any cause'.
- Failure-free survival [ Time Frame: 30 years ]Failure will be defined as BCR-ABL elevation at 2 serial times, progression to AP/BC, loss of hematologic / cytogenetic response, any appearance of ABL kinase mutation, and clonal evolution.
Biospecimen Retention: Samples With DNA

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Ages Eligible for Study: | 15 Years and older (Child, Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria:
- All patients who are diagnosed and/or treated as chronic myeloid leukemia at Asan Medical Center
- 15 years of age and over
- All patients who give written consent according to guidelines at Asan Medical Center committee on human research
Exclusion Criteria:
- Patients who refuse to give consent to registering

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01761695
Korea, Republic of | |
Asan Medical Center | |
Seoul, Korea, Republic of, 138-736 |
Principal Investigator: | Dae-Young Kim, MD | Assistant Professor |
Responsible Party: | Dae-Young Kim, Assistant Professor, Asan Medical Center |
ClinicalTrials.gov Identifier: | NCT01761695 |
Other Study ID Numbers: |
AMC-HEMREG-CML |
First Posted: | January 7, 2013 Key Record Dates |
Last Update Posted: | July 20, 2018 |
Last Verified: | July 2018 |
Leukemia Leukemia, Myeloid Leukemia, Myelogenous, Chronic, BCR-ABL Positive Leukemia, Myeloid, Chronic-Phase Leukemia, Myeloid, Accelerated Phase Chronic Disease Neoplasms by Histologic Type |
Neoplasms Disease Attributes Pathologic Processes Myeloproliferative Disorders Bone Marrow Diseases Hematologic Diseases |