Does Deficiency in Vitamin D Induced Hypercoagulation or Thrombin Generation
Working hypothesis and aims: The aim of our study is to investigate whether vitamin D deficiency could cause increased thrombin generation and a hypercoagulable state healthy volunteers.
In total 400 healthy volunteers are planned for inclusion in this trial. After signing an informed consent two blood samples will be obtained from each participant.
Expected results: invastigator expect to find that volunteers with vitamin D deficiency will have thrombin generation curve compatible with hypercoagulable state and returning to normal after treatment with vitamin D
|Study Type:||Observational [Patient Registry]|
|Study Design:||Time Perspective: Prospective|
|Target Follow-Up Duration:||3 Months|
- the correlation between vitamin D levels and endogenous thrombin potential [ Time Frame: 3 month ] [ Designated as safety issue: No ]one blood test
|Study Start Date:||April 2013|
|Study Completion Date:||July 2013|
|Primary Completion Date:||June 2013 (Final data collection date for primary outcome measure)|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01761669
|Afula, Israel, 19101|
|Principal Investigator:||mazen elias, MD||Emek medical center|