We are updating the design of this site. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Does Deficiency in Vitamin D Induced Hypercoagulation or Thrombin Generation

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01761669
First Posted: January 7, 2013
Last Update Posted: November 3, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Elias mazen, HaEmek Medical Center, Israel
  Purpose

Working hypothesis and aims: The aim of our study is to investigate whether vitamin D deficiency could cause increased thrombin generation and a hypercoagulable state healthy volunteers.

Methods:

In total 400 healthy volunteers are planned for inclusion in this trial. After signing an informed consent two blood samples will be obtained from each participant.

Expected results: invastigator expect to find that volunteers with vitamin D deficiency will have thrombin generation curve compatible with hypercoagulable state and returning to normal after treatment with vitamin D


Condition Intervention
Cardiovascular Disease Drug: Vitamin D

Study Type: Observational [Patient Registry]
Study Design: Time Perspective: Prospective
Target Follow-Up Duration: 3 Months

Resource links provided by NLM:


Further study details as provided by Elias mazen, HaEmek Medical Center, Israel:

Primary Outcome Measures:
  • the correlation between vitamin D levels and endogenous thrombin potential [ Time Frame: 3 month ]
    one blood test


Enrollment: 400
Study Start Date: April 2013
Study Completion Date: July 2013
Primary Completion Date: June 2013 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
healthy voulnters Drug: Vitamin D

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
400 healthy volunteers
Criteria

Inclusion Criteria: age >18 healthy naive to drug treatment -

Exclusion Criteria:

no exc criteria

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01761669


Locations
Israel
HaEmekMC
Afula, Israel, 19101
Sponsors and Collaborators
HaEmek Medical Center, Israel
Investigators
Principal Investigator: mazen elias, MD Emek medical center
  More Information

Responsible Party: Elias mazen, Director of Internal Medicine C, HaEmek Medical Center, Israel
ClinicalTrials.gov Identifier: NCT01761669     History of Changes
Other Study ID Numbers: vitamin D
First Submitted: December 4, 2012
First Posted: January 7, 2013
Last Update Posted: November 3, 2016
Last Verified: December 2014

Additional relevant MeSH terms:
Cardiovascular Diseases
Vitamins
Vitamin D
Ergocalciferols
Micronutrients
Growth Substances
Physiological Effects of Drugs
Bone Density Conservation Agents